Treatment of Acute Lymphoblastic Leukemia — 30 Years’ Experience at St. Jude Children’s Research Hospital — NEJM

September 11, 2016

http://www.nejm.org/doi/full/10.1056/NEJM199310283291801#t=article

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When treated with effective multiagent chemotherapy, about two thirds of children with newly diagnosed acute lymphoblastic leukemia survive for long periods of time1-4. Much of this success can be credited to more intensive early treatment, especially of patients at higher risk of relapse.
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Result of Pinkel ’79 study