Posts Tagged ‘cmptxn’

A wider field of view to predict expression | Nature Methods

November 10, 2021

A gene sequence-to-expression machine learning model achieves improved accuracy by incorporating information about potential long-range interactions.

Yang Young Lu and William Staford Noble

https://www.nature.com/articles/s41592-021-01259-4

Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors : Nature Genetics : Nature Research

May 6, 2017

http://www.nature.com/ng/journal/v49/n5/full/ng.3818.html

Ref component analysis..of transcriptomes, by @Robson_Paul &co http://www.Nature.com/ng/journal/v49/n5/full/ng.3818.html Clustering similarity of samples to tissue references

Evolution of Bow-Tie Architectures in Biology

April 28, 2017

Evolution of BowTie Architectures http://journals.PLOS.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004055 3-layer, in-mid-out systems can have small a waist when their goal is compressible

Species-Specific | The Scientist Magazine(R)

September 6, 2015

Scientists uncover striking differences between mouse and human gene expression across a variety of tissues.
By Jyoti Madhusoodanan | November 17, 2014

http://www.the-scientist.com/?articles.view/articleNo/41453/title/Species-Specific/

QT:{{”
The results “go a little against the grain,” said bioinformatician Mark Gerstein of Yale University who was not involved in the study. “We might think that humans and mice are very similar [genetically], but when we compare their transcriptomes, they’re more different than we thought.”
“}}

Lessons from modENCODE

July 11, 2015

http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090413-025448

Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo

April 5, 2015

Circadian #Enhancers Coordinate… Rhythmic… Transcription http://www.cell.com/cell/abstract/S0092-8674%2814%2901310-5
Periodicity helps find #eRNAs/enhancers & their targets

Tiny, Vast Windows Into Human DNA – NYTimes.com

September 6, 2014

http://www.nytimes.com/2014/09/02/science/human-fly-worm-dna.html

Genomics Links Humans to Insects – PNC Voice | PNC Voice

September 6, 2014

http://www.thepncvoice.com/genomics-links-humans-insects/34865

In humans, worms and flies, shared genetics | Yale Daily News

September 5, 2014

http://yaledailynews.com/blog/2014/09/02/in-humans-worms-and-flies-shared-genetics/

Expanding ENCODE | The Scientist Magazine(R)

August 31, 2014

http://www.the-scientist.com//?articles.view/articleNo/40891/title/Expanding-ENCODE