Posts Tagged ‘microbiome’

Immune Disorders and Autism – NYTimes.com

June 19, 2017

QT:{{”
“For people, a drug that’s safe for use during pregnancy may help. A probiotic, many of which have anti-inflammatory properties, may also be of benefit. Not coincidentally, asthma researchers are arriving at similar conclusions; prevention of the lung disease will begin with the pregnant woman. Dr. Parker has more radical ideas: pre-emptive restoration of “domesticated” parasites in everybody — worms developed solely for the purpose of correcting the wayward, postmodern immune system.

Practically speaking, this seems beyond improbable. And yet, a trial is under way at the Montefiore Medical Center and the Albert Einstein College of Medicine testing a medicalized parasite called Trichuris suis in autistic adults.

First used medically to treat inflammatory bowel disease, the whipworm, which is native to pigs, has anecdotally shown benefit in autistic children.

And really, if you spend enough time wading through the science, Dr. Parker’s idea — an ecosystem restoration project, essentially — not only fails to seem outrageous, but also seems inevitable.”
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Your Microbe Aura Could Be as Distinctive as Your Fingerprint – The Atlantic

August 19, 2016

Your Microbe Aura Could Be as Distinctive as Your Fingerprint http://www.theatlantic.com/health/archive/2015/09/inside-the-germ-cloud/406591 Pot. #privacy risk, but will we see microbiome perfume

Scientists Urge National Initiative on Microbiomes – The New York Times

February 29, 2016

http://www.nytimes.com/2015/10/29/science/national-initiative-microbes-and-microbiomes.html

Dietary modification of the microbiome affects risk for cardiovascular disease. – PubMed – NCBI

February 10, 2016

http://www.ncbi.nlm.nih.gov/pubmed/23656565

Microbiome Fingerprints | The Scientist Magazine(R)

May 17, 2015

http://www.the-scientist.com/?articles.view/articleNo/42950/title/Microbiome-Fingerprints/

QT:{{”

As microbiome signatures mature, law enforcement or intelligence agents could theoretically track people by looking for traces of them left in the microbes they shed. Mark Gerstein, who studies biomedical informatics at Yale University and was not involved in the new study, suggested, for instance, that one could imagine tracking a terrorist’s movements through caves using their microbiome signature.

Huttenhower and his colleagues were identifying individuals out of pools of just hundreds of project participants, however. It is currently unclear how well the algorithm will perform when applied to the general population, though the researchers estimate that their code could likely pick someone out from a group of 500 to 1,000. “I would expect that number to get bigger in the future as we get more data and better data and better coding strategies,” Huttenhower said.

But the work raises privacy concerns similar to those faced by scientists gather human genomic data. Microbiome researchers are already wary of the human genomic DNA that gets caught up in microbiome sequences, but it increasingly appears that the microbiome sequences themselves are quite personal.

In the genomics field, researchers have increasingly limited access to databases containing human genomic sequencing data. Researchers must apply to use these data. “People might increasingly want to put the microbiome data under the same type of protection that they put normal genomic variants under,” said Gerstein. “Your microbiome is associated with various disease risks and proclivities for X and Y. I don’t think it’s a completely neutral identification. It potentially says things about you.”

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Identifying personal microbiomes using metagenomic codes

May 17, 2015

Identifying personal microbiomes using metagenomic codes
http://www.pnas.org/content/early/2015/05/08/1423854112.abstract Pot. tracking & #privacy implications
http://www.the-scientist.com/?articles.view/articleNo/42950/title/Microbiome-Fingerprints

http://www.pnas.org/content/early/2015/05/08/1423854112.abstract

doi: 10.1073/pnas.1423854112

Identifying personal microbiomes using metagenomic codes

Eric A. Franzosa
Katherine Huang
James F. Meadow
Dirk Gevers
Katherine P. Lemond
Brendan J. M. Bohannanc
Curtis Huttenhower

Longitudinal analysis of microbial interaction between humans and the indoor environment

May 3, 2015

Microbial interaction betw humans & the indoor environment http://www.sciencemag.org/content/345/6200/1048.abstract
Unique personal signatures w/ implications for #forensics

Places change to conform to signature…..

Cheese Rind Communities Provide Tractable Systems for In Situ and In Vitro Studies of Microbial Diversity

March 29, 2015

Scientists & cheesemakers gather for (microbial) culture
http://www.nature.com/news/scientists-and-cheesemakers-gather-for-microbial-culture-1.15776 #Cheese is big for #microbiome differences one can taste

Also: http://www.sciencedirect.com/science/article/pii/S0092867414007454

Microbiologists are on a quest to catalogue and control the bacteria that make each raw-milk cheese unique.
Ewen Callaway
27 August 2014

Syntrophic exchange in synthetic microbial communities

March 28, 2015

Syntrophic exchange in synthetic #microbial communities [& their evolution] http://www.pnas.org/content/111/20/E2149.abstract Trading metabolically costly amino acids

The Excrement Experiment – The New Yorker

February 22, 2015

The Excrement Experiment
http://www.newyorker.com/magazine/2014/12/01/excrement-experiment Fecal transplants have been successful against disease but should they be considered a #drug

Medical Dispatch DECEMBER 1, 2014 ISSUE
The Excrement Experiment
Treating disease with fecal transplants.
BY EMILY EAKIN