Posts Tagged ‘x78qtcore’

cybersecurity story

August 5, 2017

The absent-minded prof in the news…!

Cybersecurity for the travelling scientist

Virtual private networks, tracking apps and ‘burner’ laptops: how to protect sensitive data when you take your research on the road.

Brian Owens

02 August 2017

Mark Gerstein has had his fair share of scares when it comes to losing track of his electronic devices — and, along with them, access to his private information and research data.

“I’m very security conscious, but also a bit of an absent-minded professor,” says Gerstein, a bioinformatician at Yale University in New Haven, Connecticut.

He recalls one trip to Boston, Massachusetts, when he left his phone in a taxi, and watched it get farther and farther away on the tracking app on his iPad while he ran after the car in vain. Luckily, Gerstein was able to contact the taxi company, and eventually watched his phone make the return journey to his pocket.

Gerstein’s story had a happy ending, but all too often, hardware lost on the road is lost for good.


YaleNews | Research in the news: Catalogue of human genetic variation revealed

September 30, 2015

Geneticists tap human knockouts

November 1, 2014

Sequenced genomes reveal mutations that disable single genes and can point to new drugs.

Ewen Callaway

28 October 2014 Corrected:
29 October 2014

You should also read the Corrections to this article


The poster child for human-knockout efforts is a new class of drugs that block a gene known as PCSK9 (see Nature 496, 152–155; 2013). The gene was discovered in French families with extremely high cholesterol levels in the early 2000s. But researchers soon found that people with rare mutations that inactivate one copy ofPCSK9 have low cholesterol and rarely develop heart disease. The first PCSK9-blocking drugs should hit pharmacies next year, with manufacturers jostling for a share of a market that could reach US$25 billion in five years.

“I think there are hundreds more stories like PCSK9 out there, maybe even thousands,” in which a drug can mimic an advantageous
loss-of-function mutation, says Eric Topol, director of the Scripps Translational Science Institute in La Jolla, California. Mark Gerstein, a bio­informatician at Yale University in New Haven, Connecticut, predicts that human knockouts will be especially useful for identifying drugs that treat diseases of ageing. “You could imagine there’s a gene that is beneficial to you as a 25-year-old, but the thing is not doing a good job for you when you’re 75.”


Genomics Researchers Imagine their Ideal Computer

December 9, 2013

Paul Basken
The Chronicle of Higher Education

BioTechniques – The Myth of the Single Genome

October 21, 2013

BioTechniques – The Myth of the Single Genome

The Myth of the Single #Genome: fetal Y chr left in women + smaller microchimerism in specific tissues MT @xberthet

Navigating Collaborative Grant Research | Science Careers

October 12, 2013

A post in Science Careers discussed type of collaborative environment in the lab.

Poking Holes in Genetic Privacy –

June 17, 2013

June 16, 2013
Poking Holes in Genetic Privacy

Not so long ago, people who provided DNA in the course of research studies were told that their privacy was assured. Their DNA sequences were on publicly available Web sites, yes, but they did not include names or other obvious identifiers. These were research databases, scientists said, not like the forensic DNA banks being gathered by the F.B.I. and police departments.

Experts were startled by what Dr. Erlich had done. “We are in what I call an awareness moment,” said Eric D. Green, director of the National Human Genome Research Institute at the National Institutes of Health.

Research subjects who share their DNA may risk a loss of not just their own privacy but also that of their children and grandchildren, who will inherit many of the same genes, said Mark B. Gerstein, a Yale professor who studies large genetic databases.

Big biology: The ’omes puzzle : Nature News & Comment

March 1, 2013
Where once there was the genome, now there are thousands of ’omes.
Nature goes in search of the ones that matter.
by Monya Baker
27 February 2013Contains an interesting ‘omes crossword

Junk no more > Features > Winter 2013 | Yale Medicine

February 28, 2013 Yale scientists played a leading role in an international effort to map the 99 percent of the human genome that doesn’t produce
proteins—perhaps ending the notion that those regions are “junk.” By Colleen Shaddox

Big biology: The ’omes puzzle : Nature News & Comment

February 28, 2013 Where once there was the genome, now there are thousands of ’omes. Nature goes in search of the ones that matter.
by Monya Baker
27 February 2013