Posts Tagged ‘pod57’
TWiEVO 9: How to crash your gene drive
July 5, 2016
Hosts: Nels Elde and Vincent Racaniello
Guest: Jim Bull
Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve.
TOR: Not so Anonymous https://twit.tv/shows/security-now/episodes/493 Illustrates how traffic stats & metadata are more important for Security Now than #encryption
Some quick thoughts after listening to first 9 episodes
“Will Musicians Survive in the Age of Free When the “Bottle” is worth more than the wine” – a great line & an observation that the spotify platform is worth more than its music . See also:
“Intent, Licenses and “Sweat of the Brow” – helpful discussion of copyright but it would have been nice to hear about copyleft & re-combining of artworks
“two letters and a number” – MP3.com was originally someone’s name. Robertson’s story how on how to be sued & wooed simultaneously
“so… Why does Liza Minnelli get paid when the Sex Pistols Stream?” – how to weight things (downloads or listeners) & various frauds based on this…
Can you Sell Something that Doesn’t Exist? – Superfans: would you rather collect unemployment or by the latest Doors album?
enjoyed all these episodes from the Mendelspod podcast (http://mendelspod.com/)
Affymetrix CEO, Frank Witney, on Arrays in the Age of Sequencing 22:40 3/10/15
Rare Disease Horizons: The Hope of New Research and Technology, Part II: Other Omics with Mike Snyder, Stanford 22:20 5/9/14
In Partnership with IBM’s Watson, Pathway Genomics Reinvents Itself 16:02 3/12/15
Short Read Sequencing Not Up to the Task of Characterizing
Transcriptome Says Mike Snyder of Stanford 26:46 9/10/14
The Sports Genes with Jeremy Koenig, Athletigen 22:32 6/4/15
Want Answers? Look to the Non-Coding Region of the Genome, Says Cancer Researcher, Tim Triche 24:45 7/9/15
Bina CEO Details Secret to Success in NGS Informatics 26:29 7/17/15
New York Genome Center’s Nathan Pearson on Public Outreach for Genomics 32:49 8/19/15
In search of the physical internet
100 Years of #Atomic Theory: explains why deriving the #Rydberg const. from more fundamental ones was so important
Best Season to Get #Pregnant: not May. Unfortunately, winter babies will suffer more #healthproblems!
We’ve known for a long
time that summer babies are healthier than winter babies but not the why. …
Right. And these are babies that are born in the summer versus those that are born in the
winter. There’s been this correlation that’s been around for a long time. Scientists have
seen that children that are born in the winter tend to have more health problems later in
life. They tend to be slower growers, have higher incidences of mental illness, and even
Around 12 July interesting discussion of correlation between the months of ones birth and later
health problems. Winter born children are more susceptible to health problems. The theory
proposed is that this has to due with flu and the shortening and premature birth.
Battle for the Americas: between N & S American #fauna coming together after the Isthmus of Panama was formed 3 Mya
Alfred Russel Wallace, the father of biogeography, recognized the faunal melting pot created when the tip of Central America collided with South America and forged the Isthmus of Panama, and in 1876 he postulated what is now called the Great American Biotic Interchange. The story has a dark ending: South American fauna compete poorly at home and away, and many species go extinct.
Interesting discussion of the Isthmus of Panama. The Isthmus was formed about three million years ago from volcanic action and divided the two oceans. It allowed two very different groups of fauna, that from North America and that from South America to come together. Most of the South American fauna expired as predicted by Wallace.
So this is a therapy that goes by a somewhat unwieldy name of CAR T cell therapy….
So it’s sort of combining a few different types of
therapy; it’s the gene therapy, although the genetic modifications happen outside of the
person’s body, that’s one piece. It’s what’s called an immunotherapy, which means it’s
trying to kind of harness the immune system to fight cancer. And it’s also highly
personalized because every patient’s therapy is their own; you can’t just create T cells
and give them to everybody, it’s sort of a unique batch for each patient. “}}
Dizzying Journey to a New #Cancer Arsenal: CAR Tcell therapy combines gene therapy, immunotherapy & personalization into an effective treatment for ~$50K