Posts Tagged ‘pod57’

Computationally-designed synthetic protein assemblies that evolve like viruses | Nature Research Microbiology Community

May 22, 2018

Evolution of a designed protein assembly encapsulating its own RNA genome The opposite, in a sense, of #BioInspired. Computational design of man-made virus capsid


Computationally-designed synthetic protein assemblies that evolve like viruses | Nature Research Microbiology Community

Cryo-EM structure of substrate-bound human telomerase holoenzyme | Nature

April 28, 2018

#CryoEM structure of substrate-bound human telomerase holoenzyme Quote: “2 flexibly RNA-tethered lobes: the catalytic core (w/ #TERT & conserved motifs of telomerase RNA) & an H/ACA RNP”

Could baby’s first bacteria take root before birth?

April 21, 2018

Could baby’s first bacteria take root before birth? Interesting discussion of the controversy around detecting trace exogenous sequences in human tissues. Perhaps relevant to #exRNA?

Need to make a molecule? Ask this AI for instructions

April 7, 2018

Need to make a molecule? Ask this AI for instructions #DeepLearning to do better #retrosynthesis. Perhaps other things in chemistry could be learned as well!

“The tool, described in Nature on 28 March1, is not the first software to wield artificial intelligence (AI) instead of human skill and intuition. Yet chemists hail the development as a milestone, saying that it could speed up the process of drug discovery and make organic chemistry more efficient.

“What we have seen here is that this kind of artificial intelligence can capture this expert knowledge,” says Pablo Carbonell, who designs synthesis-predicting tools at the University of Manchester, UK, and was not involved in the work. He describes the effort as “a landmark paper”.”

The Moth | Stories | Data Mining for Dates

December 6, 2016

Nels Elde podcast

November 21, 2016

TWiEVO 9: How to crash your gene drive
July 5, 2016
Hosts: Nels Elde and Vincent Racaniello
Guest: Jim Bull
Nels and Vincent speak with Jim Bull about the results of genetic models which suggest that the evolution of inbreeding in response to lethal gene drive might make population control difficult to achieve.

Security Now 493 TOR: Not so Anonymous | TWiT

March 24, 2016

TOR: Not so Anonymous Illustrates how traffic stats & metadata are more important for Security Now than #encryption

21khz: The Art of Money In Music

December 31, 2015

Some quick thoughts after listening to first 9 episodes

“Will Musicians Survive in the Age of Free When the “Bottle” is worth more than the wine” – a great line & an observation that the spotify platform is worth more than its music . See also:

“Intent, Licenses and “Sweat of the Brow” – helpful discussion of copyright but it would have been nice to hear about copyleft & re-combining of artworks

“two letters and a number” – was originally someone’s name. Robertson’s story how on how to be sued & wooed simultaneously

“so… Why does Liza Minnelli get paid when the Sex Pistols Stream?” – how to weight things (downloads or listeners) & various frauds based on this…

Can you Sell Something that Doesn’t Exist? – Superfans: would you rather collect unemployment or by the latest Doors album?

Mendelspod podcast

September 6, 2015

enjoyed all these episodes from the Mendelspod podcast (

Affymetrix CEO, Frank Witney, on Arrays in the Age of Sequencing 22:40 3/10/15

Rare Disease Horizons: The Hope of New Research and Technology, Part II: Other Omics with Mike Snyder, Stanford 22:20 5/9/14

In Partnership with IBM’s Watson, Pathway Genomics Reinvents Itself 16:02 3/12/15

Short Read Sequencing Not Up to the Task of Characterizing
Transcriptome Says Mike Snyder of Stanford 26:46 9/10/14

The Sports Genes with Jeremy Koenig, Athletigen 22:32 6/4/15

Want Answers? Look to the Non-Coding Region of the Genome, Says Cancer Researcher, Tim Triche 24:45 7/9/15

Bina CEO Details Secret to Success in NGS Informatics 26:29 7/17/15

New York Genome Center’s Nathan Pearson on Public Outreach for Genomics 32:49 8/19/15

Behind the Glowing Screen | Amherst College

May 31, 2014

In search of the physical internet