Posts Tagged ‘x78retwee’

Conquering Alzheimer’s: a look at the therapies of the future

May 29, 2023

https://www.nature.com/articles/d41586-023-00954-w

lecanemab is one of the new drugs

Interesting New Privacy Papers

May 29, 2023

the authors used deep sequencing of environmental DNA (eDNA) to find human genomic information, which they called human genetic bycatch (HGB). This paper was published in Nature Ecology & Evolution. https://www.nature.com/articles/s41559-023-02056-2

This study was also featured in an article in the New York Times.

https://www.nytimes.com/2023/05/15/science/environmental-dna-ethics-privacy.html

A new class of drugs for weight loss could end obesity | The Economist

April 28, 2023

https://www.economist.com/briefing/2023/03/02/a-new-class-of-drugs-for-weight-loss-could-end-obesity
GLP-1 agonists :
wegovy ozempic mounjaro

https://www.ncbi.nlm.nih.gov/books/NBK551568/#:~:text=Glucagon%2Dlike%20peptide%2D1%20agonists,and%20contraindications%20for%20these%20drugs. QT:{{”
Mechanism of Action
Glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GIP), both incretin hormones inactivated by dipeptidyl peptidase-4 (DPP-4), stimulate insulin secretion after an oral glucose load via the incretin effect.[10][11] In type 2 diabetes, this process can become blunted or even be absent; however, the utilization of pharmacological levels of GLP-1 can revive insulin excretion. The benefits of this form of therapy to treat type 2 diabetes include delayed gastric emptying and inhibiting the production of glucagon from pancreatic alpha cells if blood sugar levels are high.
“}}

Leaving LastPass

March 26, 2023

https://twit.tv/shows/security-now/episodes/904?autostart=false

Found the whole @LastPass debacle depressing. First, I trusted [Steve Gibson’s] endorsement. Then I trusted it. Now I’m unsure what to do.

Bitwarden? 1password ?

What ChatGPT and generative AI mean for science

February 12, 2023

Is it possible to determine how many new sentences & ideas are introduced vs just phrase-scale grammatical and stylistic fixes?

https://www.nature.com/articles/d41586-023-00340-6

Even a Little Alcohol Can Harm Your Health, Research Shows – The New York Times

January 24, 2023

Note that the article didn’t mention the connection between alcohol, stomach acid, GERD & esophageal cancer. Isn’t this another negative of alcohol besides its relationship to DNA damage?

https://www.nytimes.com/2023/01/13/well/mind/alcohol-health-effects.html

What most surprised experts about the Covid pandemic – STAT

January 22, 2023

20/20 hindsight & 20/200 foresight
https://www.statnews.com/2022/12/27/covid19-pandemic-what-most-surprised-experts/

Opinion | The XBB.1.5 variant shows the coronavirus is not done with us – The Washington Post

January 12, 2023

I’m listening

https://www.washingtonpost.com/opinions/2023/01/08/xbb-covid-variant-immune-evasive-pandemic/

The Friendship That Made Google Huge | The New Yorker

January 9, 2023

https://twitter.com/ItaiYanai/status/1611161045011161089

https://www.newyorker.com/magazine/2018/12/10/the-friendship-that-made-google-huge

The Marvels—And Mistakes—Of Supertall Skyscrapers – The Atlantic

January 1, 2023

Great article. Thought the very intentional “wind shaping” was fascinating (e.g. the “blow through” floors at 432 Park). Maybe we’ll see fins next.

QT:{{”
This didn’t seem unrelated to a lawsuit that 432 Park’s condo board has filed against the building’s developer. The plaintiffs claim that the building is riddled with more than 1,500 defects that have led to leaks, cracks, electrical explosions, and elevator shutdowns that trapped people for hours—as well as “horrible and obtrusive noise and vibrations,” including clicks, creaks, and a trash chute that thunders “like a bomb.”
….
diffusing the suction-filled whirlpools that sway a building as wind whips around its sides. You could notch the corners, like on Taipei 101, which resembles a towering stack of gifts. You could twist the building, like the Twizzler-esque Shanghai Tower. You could taper it to look like the tip of a paintbrush, like the Lakhta Center, or cut out sections to let wind blow through it, like the Shanghai World Financial Center, which is nicknamed “The Bottle Opener.” 432 Park’s designers decided to make it more porous: Every 12 stories, there are two “blow through” floors with cutouts for windows, but no glass. “}}

https://www.theatlantic.com/magazine/archive/2023/01/supertall-mega-skyscraper-building-nyc/672228

steinway tower
https://www.dropbox.com/s/soza3usm060fzya/steinway-tower-view.docx?dl=0