Posts Tagged ‘clipcacheondisk’

Longevity diet: How changing what you eat could add decades to your life | New Scientist

September 17, 2022

https://www.newscientist.com/article/mg25533930-400-a-longevity-diet-that-hacks-cell-ageing-could-add-years-to-your-life/

https://www.dropbox.com/s/gz666mkgv912lyl/2022-09-04%2023.12.45.New-Scientist-Longevity-Diet.clipcacheondisk.pdf?dl=0

clipcach

Limit calorie intake to maintain a body mass index of 22to 23 for men and 21 to 22 for women.

QT:{{”
Eat a diet high in whole grains, legumes and nuts. Stop eating meat to restrict Intake of the amino acid methionine, but include some fish.

Aim to get between 45 and 60 per cent of calories from non-refined complex carbohydrates, 10 to 15 per cent from plant-based proteins and 25 to 35 per cent from plant-based fats

Do a limited daily fast, eating no calories from around 3 hours before bedtime and for the next 11 to 12 hours.

Every two to three months, undertake five days of complete fasting or a fasting-mlmicking diet

Low alcohol
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iPad Notebook export for Overloaded: How Every Aspect of Your Life is Influenced by Your Brain Chemicals

August 14, 2022

https://www.goodreads.com/notes/57593893-overloaded/114528832-mark-gerstein?ref=bsop

How ‘Trustless’ Is Bitcoin, Really? – The New York Times

June 18, 2022

QT:{{”
Mark Gerstein, a professor of bioinformatics at Yale University, found in the research implications for data privacy. He recently stored a genome on a private blockchain, which allowed for a secure and tamperproof record. But he noted that in a public setting, as with Bitcoin’s blockchain, a data set’s size and subtle patterns made it susceptible to breaches, even as the data remained immutable. (Ms. Blackburn wasn’t tampering with the Bitcoin blockchain’s records.)

“That’s the amazing thing about big data,” Dr. Gerstein said. “If you have a big enough data set, it starts to leak information in unexpected ways.” Even more so when data from different sources are connected, he said: “When you combine one data set with another to make a bigger data set, nonobvious linkages can arise.”
“}}

https://www.nytimes.com/2022/06/06/science/bitcoin-nakamoto-blackburn-crypto.html

2022-06-08-09.34.24.NY-Times-story-on-bitcoin.x78qt.jpg
2022-06-08-09.36.23.NY-Times-story-on-bitcoin.x78qt.jpg

iPhone Notebook export for The Performance Cortex: How Neuroscience Is Redefining Athletic Genius

April 30, 2022

Your Notebook exported from The Performance Cortex: How Neuroscience Is Redefining Athletic Genius

https://www.goodreads.com/notes/36560373-the-performance-cortex/114528832-mark-gerstein?ref=h_cr

“The Man From the Future,” Reviewed: John von Neumann Thought He Had the Answers | The New Republic

March 27, 2022

https://newrepublic.com/article/165581/john-von-neumann-man-from-future-book-review

Hybrid labs piece went up on Friday

March 14, 2022

https://twitter.com/KendallSciWrite/status/1503508908085760000

CAREER FEATURE
11 March 2022

How hybrid working took hold in science

Two years since COVID-19 forced labs to shut down, group leaders describe how academic research has changed, perhaps forever. Kendall Powell

https://www.nature.com/articles/d41586-022-00729-9

QT:{{”

Principal investigators (PIs), including those who started research groups during the pandemic, are now incorporating the best parts of pandemic flexibility into the future of research. “It’s hard to see any good when we are heading toward six million deaths,” says Mark Gerstein, a computational biologist at Yale University in New Haven, Connecticut. “But the pandemic has taught us new ways of thinking about things.”

For example, Gerstein has learnt that some group members work most efficiently at home, whereas others really need to come in to work. “I have been a little surprised that the tails of that spectrum have been so wide.”

Gerstein says that increased flexibility should also help to ease some of the thorniest problems that early-career researchers can face, such as childcare support and the two-body problem — the challenge of two partners needing to find a job in the same geographical location. “I want to be very flexible,” Gerstein says. “That’s what talented people want in their workplace.”
….

Hybrid lab working has also changed the dynamics of groups. Gerstein’s weekly Zoom meeting with his 40-strong team can last for several hours, but he’s fine with a healthy dose of zoning out, turning cameras off and multitasking for those who don’t need to engage in the main conversation. His group uses a Google Doc to draw up the agenda and the members share screens to annotate it in real time. He then saves the final document to the lab’s Dropbox account.

Science-ing from home

“It is efficient and works even better than in-person meetings,” says Gerstein, who plans to retain video meetings to accommodate childcare responsibilities, illness and scheduling conflicts. “Now, everyone is equal, even our collaborators in Europe or China. I don’t think we’ll ever go back to a large in-person lab meeting.”

Gerstein has also been rethinking his computational group’s workspace. “Do we want that same traditional look where people come in every day and sit at desks?” he asks. “I’m sceptical — no one wants to be in open-plan cubes.”

Instead, he sees his lab of the future as being one in which, ideally, researchers have their own office and can close the door when they need to think, code or write. There also needs to be a room big enough for three or four people, to host meetings or conference calls. Hybrid working could mean a lot of unoccupied space on certain days. He’s considering a ‘hotelling’ option, with lab members booking larger office spaces in advance as needed, alongside everyone having a smaller dedicated workstation in the group’s shared space.

“}}

Why world leaders are refusing to give Russia their DNA | The Week UK

March 6, 2022

https://www.theweek.co.uk/news/world-news/russia/955813/why-world-leaders-refuse-give-russia-dna

Thought this story was intriguing in relation to genomic #privacy & how the pandemic has potentially amplified worries about it. It was presaged by an opinion piece we did a decade ago
(https://USAToday.com/story/opinion/tory/opinion/2013/06/27/dov-greenbaum-and-mark-gerstein-on-nsa-and-genetics/2465589)

https://twitter.com/MarkGerstein/status/1500693248179904513

Mutation bias reflects natural selection in Arabidopsis thaliana | Nature

February 5, 2022

https://www.nature.com/articles/s41586-021-04269-6

The power of genetic diversity in genome-wide association studies of lipids | Nature

January 10, 2022

https://www.nature.com/articles/s41586-021-04064-3

some focus on its main method
MR-MEGA
https://academic.oup.com/hmg/article/26/18/3639/3976569

Selection of good quotes from The Man from the Future

January 8, 2022

At the link below are a selection of good quotes from
The Man from the Future: The Visionary Life of John von Neumann Hardcover by Ananyo Bhattacharya (Author)

https://docs.google.com/document/d/1FIM00rGx28S0Z6cQiNhwAm8otpdphRttdabA03hPWgY/edit

(public doc: Selected-Good-Quotes-from-Man-from-the-Future–jvn0mg)

Further quotes I liked are at:

https://docs.google.com/document/d/1noMiAy2maVVyPh94rEzEZbCwR6TPjZ2T223Hm5ylDZ0/edit

(a private doc: Full-List-of-Good-quotes-from-Man-from-the-Future–jvn0mg)