Posts Tagged ‘mynotes0mg’

Sigma Xi Conference this Week

October 30, 2018

My notes from the Sigma Xi Conference

LECTURES

http://lectures.gersteinlab.org/summary/Using-population-scale-functional-genomics-mental-disease-n-exploiting-data-exhaust-20181025-i0sigma/

http://lectures.gersteinlab.org/summary/Thoughts-on-Annotation-Variants-Application-disease-context–20182310-i0sigma+ucsf/

TWEETS

Favorited-Tweets-from-i0sigma-meeting.xlsx

https://docs.google.com/spreadsheets/d/e/2PACX-1vQ9yzRc3_Dl0bUJ5K4oxNAdLjNdZYiMk-LuZTYxn-3Spmli94nc15x4zd_lUiw3NX4BxOZNqryQ462J/pubhtml

http://meetings.gersteinlab.org/2018/10.30/Favorited-Tweets-from-i0sigma-meeting.xlsx

http://meetings.gersteinlab.org/2018/10.30/printout-of-liked-tweets-from-i0sigma.pdf

LINKS

https://linkstream2.gerstein.info/tag/i0sigma/

OTHER

Slides (Private)

http://meetings.gersteinlab.org/2018/10.30/For%20labdropbox%20-%20Many%20slide%20pics%20from%20SigmaXi%20meeting%20-%20i0sigma%20–/

Modeling RNA Secondary Structure with Sequence Comparison and Experimental Mapping Data: Biophysical Journal

August 18, 2018

Modeling RNA Secondary Structure with Sequence Comparison &
Experimental Mapping Data
https://www.Cell.com/biophysj/fulltext/S0006-3495(17)30689-6 combines TurboFold sec. structure prediction w/ results of SHAPE assays

Zhen Tan
Gaurav Sharma
David H. Mathews

Open Archive Published:July 20, 2017
DOI:https://doi.org/10.1016/j.bpj.2017.06.039

Journal Club by JG

July 27, 2018

TWAS of 229k women identifies new candidate susceptibility genes for breast cancer https://www.Nature.com/articles/s41588-018-0132-x Metascan approach. Derive model for imputing transcriptome from #GTEx & validate against TCGA. Application to BCAC.

Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder | Nature Neuroscience

July 27, 2018

Genome-wide prediction & functional characterization of the genetic basis of autism spectrum disorder, by @OlgaTroyanskaya lab
https://www.Nature.com/articles/nn.4353 Intersected candidate #ASD genes w/ #BrainSpan gene expression to find a pre-natal signal for the disease

My notes from ISMB 2018 – i0ismb18

July 15, 2018

Liked Tweets

https://docs.google.com/spreadsheets/d/e/2PACX-1vRRXndiFoAnxu5A6NThwRBwcWhKuvShUtjL-ol0LE3NfVMW7KC_hC17-512LmJhsMAeZIPm4beRVtIa/pubhtml

My talk

http://lectures.gersteinlab.org/summary/RADAR-Annot-prioritization-var-20180708-i0ismb18/

Links

https://linkstream2.gerstein.info/tag/i0ismb18

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito

June 29, 2018

Creation & selection of mutations resistant to a #GeneDrive over mult. generations in the malaria mosquito
http://journals.PLoS.org/plosgenetics/article?id=10.1371/journal.pgen.1007039 Indels created by #NHEJ-based repair of DS breaks give rise to resistance (probably resulting from mis-matches due to
micro-homologies near breakpts)

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito

June 29, 2018

Creation & selection of mutations resistant to a #GeneDrive over mult. generations in the malaria mosquito
http://journals.PLoS.org/plosgenetics/article?id=10.1371/journal.pgen.1007039 Indels created by #NHEJ-based repair of DS breaks give rise to resistance (probably resulting from mis-matches due to
micro-homologies near breakpts)

Today: Jason Moore, Computational Biology and Bioinformatics speaker, 6-6-18 in BML Auditorium at 4 pm

June 7, 2018

https://linkstream2.gerstein.info/tag/talk20180606/
https://twitter.com/MarkGerstein/status/1004566413036617728

Papers for Journal Club

June 7, 2018

Alternative evolutionary histories in the sequence space of an ancient protein https://www.Nature.com/articles/nature23902 Great viz of different potential but not necessarily realized evolutionary trajectories. Quite relevant for molecular #evolution & #pseudogenes

Paper for Journal Club Tomorrow

May 22, 2018

Susceptibility of brain atrophy to TRIB3 in #Alzheimer’s disease, evidence from functional prioritization in imaging genetics
http://www.PNAS.org/content/115/12/3162.long Nice connection of developing phenotypes from #imaging, combined w. simple polygenic scores from genotypes