Posts Tagged ‘psychencode’

Genomic Data from 2,000 Brains Provides Roots of Schizophrenia, Autism – Market Research Chronicle

September 14, 2019

https://marketresearchchronicle.com/2019/09/11/genomic-data-from-2000-brains-provides-roots-of-schizophrenia-autism/

GWAS ATLAS resource

August 24, 2019

A global overview of pleiotropy and genetic architecture in complex traits

Kyoko Watanabe, Sven Stringer, Oleksandr Frei, Maša Umićević Mirkov, Christiaan de Leeuw, Tinca J. C. Polderman, Sophie van der Sluis, Ole A. Andreassen, Benjamin M. Neale & Danielle Posthuma

https://www.nature.com/articles/s41588-019-0481-0

Single Cell Resource for Mouse

August 2, 2019

QT:{{”

Tabula Muris is a compendium of single cell transcriptome data from the model organism Mus musculus, containing nearly 100,000 cells from 20 organs and tissues. The data allow for direct and controlled comparison of gene expression in cell types shared between tissues, such as immune cells from distinct anatomical locations. They also allow for a comparison of two distinct technical approaches: “}}

https://tabula-muris.ds.czbiohub.org/

SHANK3 | Spectrum | Autism Research News

July 19, 2019

https://www.spectrumnews.org/wiki/shank3/

From Zhu et al. Science (’18)
QT:{{”
Further analysis revealed that the ASD-associated genes SHANK2 and SHANK3, which encode synaptic scaffolding proteins at the postsynaptic density of excitatory glutamatergic synapses, exhibited earlier expression in the macaque NCX and other brain regions relative to humans (Fig. 7B).
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Alzheimer’s disease risk genes and mechanisms of disease pathogenesis

June 21, 2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234692/
Some related to mechanism

Single-cell genomics of autism

May 18, 2019

https://science.sciencemag.org/content/364/6441/685

Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia | Nature Communications

April 7, 2019

https://www.nature.com/articles/s41467-018-05379-y

The highly pleiotropic gene SLC39A8 as an opportunity to gain insight into the molecular pathogenesis of schizophrenia – Costas – 2018 – American Journal of Medical Genetics Part B: Neuropsychiatric Genetics – Wiley Online Library

April 7, 2019

https://onlinelibrary.wiley.com/doi/full/10.1002/ajmg.b.32545

assoc w. SCZ+Chron’s
protective to Parkinson’s

Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder. – PubMed – NCBI

April 7, 2019

https://www.ncbi.nlm.nih.gov/pubmed/30545852
gsp

Human Cell Atlas Method Development Community timeline

April 6, 2019

https://www.protocols.io/groups/hca