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Your DNA Can Now Be Pulled From Thin Air. Privacy Experts Are Worried. – The New York Times
May 17, 2023Quantitative GWAS & QTL studies
February 25, 2023Primer
Published: 25 January 2023
Molecular quantitative trait loci
François Aguet, Kaur Alasoo, Yang I. Li, Alexis Battle, Hae Kyung Im, Stephen B. Montgomery & Tuuli Lappalainen
Nature Reviews Methods Primers volume 3, Article number: 4 (2023)
Related to the discussion about quantitative GWAS and QTL, this primer review (and in particular box 1) is helpful in clarifying the (non) difference between the two types of studies:
https://www.nature.com/articles/s43586-022-00188-6
The statistics behind quantitative GWAS and QTL studies is the same, the only main difference might be the multiple testing correction procedure.
In general, it’s more a nomenclature distinction, as the term “QTL” is often used specifically for molecular traits.
Lynn Williams obituary
January 25, 2023Chat GPT
December 18, 2022Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization
October 13, 2022www.brimr.org/NIH_Awards/NIH_Awards.htm
October 5, 2022http://www.brimr.org/NIH_Awards/NIH_Awards.htm
Nice listing of NIH money by field & PI
Lab leaders wrestle with paucity of postdocs
September 4, 2022SLC6A4 Gene – GeneCards | SC6A4 Protein | SC6A4 Antibody
August 1, 2022https://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC6A4
QT:{{”
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression. [provided by RefSeq, May 2019]
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famous serotonin re-update transporter
linkstream2 microblog 