Posts Tagged ‘from’

Genetics of the human face: Identification of large-effect single gene variants

February 16, 2018

http://www.pnas.org/content/115/4/E676

New Theory Cracks Open the Black Box of Deep Learning

February 12, 2018

https://www.quantamagazine.org/new-theory-cracks-open-the-black-box-of-deep-learning-20170921

New Theory Cracks Open the Black Box of Deep Learning

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

February 11, 2018

http://science.sciencemag.org/content/359/6376/693.full
+
perspective
http://science.sciencemag.org/content/359/6376/619.full

Gene Expression Overlaps Among Psychiatric Disorders

Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression.

Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma | Nature Genetics

February 11, 2018

https://www.nature.com/articles/ng.3861?WT.ec_id=NG-201706&spMailingID=54145295&spUserID=MTc2NTYxNjY4OQS2&spJobID=1164335784&spReportId=MTE2NDMzNTc4NAS2

overview of the GPCR literature as indexed on Wikidata

February 8, 2018

https://twitter.com/EvoMRI/status/960633150115282944
Here’s an overview of the GPCR literature as indexed on Wikidata: https://tools.wmflabs.org/scholia/topic/Q38173

MIA Seminar Series (Primer + Talk) @ Broad

February 6, 2018

MODELS, INFERENCE & ALGORITHMS
nice seminar series
https://www.broadinstitute.org/scientific-community/science/mia/models-inference-algorithms

yogurt probiotics survival after freezing

February 5, 2018

QT:{{”
not finding very good data on how much of the bacteria will survive freezing in yogurt.
This “ask the professor” column matches intuition.
“}}

http://tuftsjournal.tufts.edu/2008/06/professor/01/

However, these two sources say there’s no loss in viability… https://www.sciencedirect.com/science/article/pii/S0022030200749277?via%3Dihub

Holcomb et al. (1991) reported that both L. acidophilus and
Bifidobacterium were able to survive and grow in soft-serve frozen yogurt after freezing [Holcomb, J.E., Frank, J.F. and McGregor, J.U. (1991), Viability of Lactobacillus acidophilus and Bifidobacterium bifidum in soft-serve frozen yogurt. Cult. Dairy Prod. J. 26, 4-5.]

pre-frozen yogurt can contain active cultures — just have to check the label.

JClub by BW on “3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets”, Genome Medicine

February 4, 2018

3D clusters of somatic mutations…reveal numerous rare mutations as functional targets
https://GenomeMedicine.BiomedCentral.com/articles/10.1186/s13073-016-0393-x Introduces 3DHotSpots, which is one of a number of recent approaches (incl. CLUMPS, Hotspot3D, Mutation3D & HotMAPS) for finding groupings of somatic SNVs via structure

Neurobiology course

January 20, 2018

Understanding the Brain: The Neurobiology of Everyday Life
https://www.coursera.org/learn/neurobiology

today’s google doodle

January 11, 2018

https://www.google.com/doodles/har-gobind-khoranas-96th-birthday