Posts Tagged ‘fromemail’

Toy rec #3

August 5, 2017

https://shop.lego.com/en-US/LEGO-NASA-Apollo-Saturn-V-21309

Lego rocket

TOTD neat trick to auto-dial conference call

August 5, 2017

http://allgaierconsulting.com/techtalk/2014/8/1/why-and-how-to-insert-a-pause-or-wait-key-on-your-iphone In summary, by saving phone numbers with a comma (2 sec pause) or semicolon (user prompt), you can automate dialing into a conference call.

cybersecurity story

August 5, 2017

The absent-minded prof in the news…!

http://www.nature.com/news/cybersecurity-for-the-travelling-scientist-1.22379

Cybersecurity for the travelling scientist

Virtual private networks, tracking apps and ‘burner’ laptops: how to protect sensitive data when you take your research on the road.

Brian Owens

02 August 2017

QT:{{”
Mark Gerstein has had his fair share of scares when it comes to losing track of his electronic devices — and, along with them, access to his private information and research data.

“I’m very security conscious, but also a bit of an absent-minded professor,” says Gerstein, a bioinformatician at Yale University in New Haven, Connecticut.

He recalls one trip to Boston, Massachusetts, when he left his phone in a taxi, and watched it get farther and farther away on the tracking app on his iPad while he ran after the car in vain. Luckily, Gerstein was able to contact the taxi company, and eventually watched his phone make the return journey to his pocket.

Gerstein’s story had a happy ending, but all too often, hardware lost on the road is lost for good.
“}}

DataScience related courses at Yale

July 27, 2017

The Research Data Consultation Group (http://researchdata.yale.edu/) has considered aggregating data science training information into a unified calendar.

Also, there’s an instruction calendar at the library
(http://csssi.yale.edu/instruction/workshop-and-instruction-calendar)

Robert Caro Fourth Volume – The Big Book, by Chris Jones – Esquire

July 25, 2017

The Big Book http://www.Esquire.com/features/robert-caro-0512 Great description of a clinical & cool but productive 4-decade relationship betw. R #Caro & his editor

LBJ #4

QT:{{”
“Gottlieb did the same math and agreed. In an industry that survives mostly by lying to itself, he is an anti-romantic, an
unsentimentalist. When he edits Caro, they sit side by side at a conference table and go through the pile in front of them, page by tattered page, Gottlieb attacking anything that reads too much like writing, too much like nostalgia or indulgence. He and Caro have mellowed with age, but they have fought bitter fights, fights that have caused people to close their office doors hundreds of feet away. “Everything to him is as serious as everything else,” Gottlieb says. “When we came to something like a semicolon, it was war.”

…Gottlieb is the taskmaster. (“I can remember when he told me, ‘Not bad,’ ” Caro says. “Once.”) Gottlieb and Caro, bound for forty years, rarely see each other socially. Theirs is a professional relationship, clear-eyed and clinical.

Yet they are also prisoners of a mutual faith. “Bob is convinced that without me, he cannot function,” Gottlieb says. “I have explained to him for years that it isn’t the truth. It isn’t the truth. But because he believes it to be true, it is true.” And Gottlieb has given over so much of his own life to Caro, has fought so hard over semicolons, because he believes something else to be true. “These books will live forever,” Gottlieb says. “We all know that.””
“}}

Robert Caro Fourth Volume – The Big Book, by Chris Jones – Esquire

July 25, 2017

The Big Book http://www.Esquire.com/features/robert-caro-0512 Great description of a clinical & cool but productive 4-decade relationship betw. R #Caro & his editor

LBJ #4

QT:{{”
“Gottlieb did the same math and agreed. In an industry that survives mostly by lying to itself, he is an anti-romantic, an
unsentimentalist. When he edits Caro, they sit side by side at a conference table and go through the pile in front of them, page by tattered page, Gottlieb attacking anything that reads too much like writing, too much like nostalgia or indulgence. He and Caro have mellowed with age, but they have fought bitter fights, fights that have caused people to close their office doors hundreds of feet away. “Everything to him is as serious as everything else,” Gottlieb says. “When we came to something like a semicolon, it was war.”

…Gottlieb is the taskmaster. (“I can remember when he told me, ‘Not bad,’ ” Caro says. “Once.”) Gottlieb and Caro, bound for forty years, rarely see each other socially. Theirs is a professional relationship, clear-eyed and clinical.

Yet they are also prisoners of a mutual faith. “Bob is convinced that without me, he cannot function,” Gottlieb says. “I have explained to him for years that it isn’t the truth. It isn’t the truth. But because he believes it to be true, it is true.” And Gottlieb has given over so much of his own life to Caro, has fought so hard over semicolons, because he believes something else to be true. “These books will live forever,” Gottlieb says. “We all know that.””
“}}

Quick comment on AI for pharma?

July 18, 2017

Please find the article at link:
https://www.pharma-iq.com/informatics/articles/is-big-pharma-really-on-cusp-of-ai-shake-out-0

Is big pharma really on cusp of AI shake-out?

By: Pharma IQ
Posted: 07/14/2017

QT:{{”

The promises of “disruptive technologies” have failed to live up to expectations in the past. For example, the development of ‘high throughput screening’ – a process that employs robotics to conduct millions of chemical, genetic and pharmacological tests in rapid time – in the 1990s failed to significantly reduce R&D inefficiencies and offered sporadic success rates.

“The major cost in drug R&D is last-phase clinical trials,” said Dr Mark Gerstein, professor of biomedical informatics at Yale University. “It is not clear whether AI can be as useful for these as it has been in target selection for the initial phases.”

“One of the first principles of data mining is that history is a good predictor of the future. AI has a track record of not living up to its expectations and therefore caution about how great its impact will be in the healthcare industry is now warranted.”
“}}

UC Berkeley and Bitmark partner to bring data donation to public health studies

May 28, 2017

UCB & @BitmarkInc partner to bring data donation to public health
studies https://Medium.com/@bitmark/uc-berkeley-and-bitmark-partner-to-bring-data-donation-to-public-health-studies-3e9a17891432 Using #blockchain to control one’s data

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

January 12, 2015

Tomasetti & Volgenstein

Science 2 January 2015:
Vol. 347 no. 6217 pp. 78-81
DOI: 10.1126/science.1260825

It’s a correlation between aggressiveness, mutations and cell division http://www.sciencemag.org/content/347/6217/78

NEw paper using BrainSpan data

January 12, 2015

The discovery of integrated gene networks for autism and related disorders

Fereydoun Hormozdiari
Osnat Penn
Elhanan Borenstein
Evan E. Eichler

Published in Advance November 5, 2014, doi:10.1101/gr.178855.114 Genome Res. 2015. 25: 142-154

QT:{{”
Motivated by this observation, we have developed a novel method that simultaneously integrates information from both PPI and coexpression networks to identify highly connected modules in both types of networks that are also enriched in mutations in cases and not in controls. We call this method MAGI, short for merging affected genes into integrated networks. MAGI is based on a combinatorial
optimization algorithm that aims to maximize the number of mutations in the modules while accounting for gene length and distribution of putative LoF and missense mutations in cases and controls. MAGI is generic and can be applied to any disease, given a list of de novo mutations in cases and relevant coexpression information. Using neurodevelopmental RNA-seq data from the BrainSpan Atlas
(http://www.brainspan.org/), we have applied it to exome sequence data generated from ASD, ID, epilepsy, and schizophrenia, providing a comprehensive comparison of common and specific gene modules for these diseases.
“}}