Posts Tagged ‘singlecell’

Single Cell Resource for Mouse

August 2, 2019

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Tabula Muris is a compendium of single cell transcriptome data from the model organism Mus musculus, containing nearly 100,000 cells from 20 organs and tissues. The data allow for direct and controlled comparison of gene expression in cell types shared between tissues, such as immune cells from distinct anatomical locations. They also allow for a comparison of two distinct technical approaches: “}}

https://tabula-muris.ds.czbiohub.org/

Single-cell genomics of autism

May 18, 2019

https://science.sciencemag.org/content/364/6441/685

Human Cell Atlas Method Development Community timeline

April 6, 2019

https://www.protocols.io/groups/hca

UMAPs

March 2, 2019

A lineage-resolved molecular atlas of C elegans embryogenesis at #singlecell resolution, w/ @JIsaacMurray, @JunhyongKim, @ColeTrapnell & B Waterston https://www.BiorXiv.org/content/10.1101/565549v1 Compares the known cell lineage of the worm to trees based on UMAP cell-type clusters. Remarkable agreement

https://twitter.com/MarkGerstein/status/1101927645145645056

A single-cell molecular map of mouse gastrulation and early organogenesis | Nature

February 28, 2019

https://www.nature.com/articles/s41586-019-0933-9

The single-cell transcriptional landscape of mammalian organogenesis

February 28, 2019

Using single-cell combinatorial indexing, we profiled the
transcriptomes of around 2 million cells derived from 61 embryos staged between 9.5 and 13.5 days of gestation, in a single experiment.

https://www.nature.com/articles/s41586-019-0969-x.epdf

Everyday Scientist ยป deconvoluting deconvolving

January 13, 2018

http://blog.everydayscientist.com/?p=517

A survey of human brain transcriptome diversity at the single cell level

June 27, 2017

Brain #transcriptome diversity at the single cell level
http://www.PNAS.org/content/112/23/7285 Has useful gene-exp. profiles of specific neural cell types

has profiles for 185 biomarker genes for 6 cell types

Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors : Nature Genetics : Nature Research

May 6, 2017

http://www.nature.com/ng/journal/v49/n5/full/ng.3818.html

Ref component analysis..of transcriptomes, by @Robson_Paul &co http://www.Nature.com/ng/journal/v49/n5/full/ng.3818.html Clustering similarity of samples to tissue references

Aging increases cell-to-cell transcriptional variability upon immune stimulation | Science

April 21, 2017

#Aging increases cell-to-cell transcriptional variability upon immune stimulation, but just for 225 up-reg. genes http://science.ScienceMag.org/content/355/6332/1433