D614G mutation
https://www.nytimes.com/2020/11/24/world/covid-mutation.html
Evidence Builds That an Early Mutation Made the Pandemic Harder to Stop
Scientists were initially skeptical that a mutation made the coronavirus more contagious. But new research has changed many of their minds.
https://www.nytimes.com/live/2020/11/09/world/covid-19-coronavirus-live-updates QT:{{”
The Food and Drug Administration has granted emergency authorization of a Covid-19 treatment made by the American pharmaceutical company Eli Lilly that was given to Chris Christie, the former New Jersey governor, when he was infected with the coronavirus.
The authorization, announced on Monday, applies only to people newly infected with the virus, and the agency said it should not be used in hospitalized patients. The treatment is approved for people 12 and older who have tested positive and are at risk for developing a severe form of Covid-19 or being hospitalized for the condition. That includes people who are over 65 and obese, the agency said — a key group that early studies have shown can benefit the most from the treatment.
Eli Lilly said that its treatment, called bamlanivimab, should be administered as soon as possible after a positive test, and within 10 days of developing symptoms.
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bamlanivimab
anosmia & sniff tests
QT:{{”
While it’s well established that the primary way people get infected with COVID-19 is from inhaling aerosol droplets, Kennedy said there is emerging evidence it’s “a lot easier” for the virus to get a grip on our internal system when it enters through the nasal passage versus the mouth.
That’s because the nasal passage tissue is rich in cells that have a certain receptor the virus attaches to.
“There’s more cells in the upper airway in the nasal passages that have high levels of receptor expression,” Kennedy explained. “So the virus is more likely to find the cell to infect, and it’s easier for the virus to infect cells sort of in the upper airway in the nasal passages than it is down in the lungs.”
….
It’s evident the nose and our sense of smell hold many answers to understanding COVID-19. It’s now clear a loss of sense of smell, known as anosmia, is one of the most common symptoms of COVID-19. Valentina Parma, chair of the Global Consortium for Chemosensory Research, said her organization’s data seems to show that anosmia is a better indicator of COVID-19 than fever.
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For this reason, she’s an advocate of objective tests to measure sense of smell, such as sniff tests. To that end, her organization has developed an online smell and sniff test which can be completed by people by using scents in their own home, such as banana or shampoo. “}}
mRNA-1273 is their candidate
https://www.genengnews.com/news/moderna-covid-19-vaccine-shows-immunogenicity-in-older-patients
https://en.wikipedia.org/wiki/Norin_10_wheat
Norin 10 provided two very important genes, Rht1 and Rht2
