Posts Tagged ‘keyabbrev’

It’s Not Every Day We Get a New Blue – The New York Times

February 14, 2021

YInMn blue
Formula: YIn1−xMnxO3

Coronavirus Variant Tracker – The New York Times

February 12, 2021

B.1.1.7, B.1.351

The D614G mutation emerged in eastern China early in the pandemic and then quickly spread around the world, displacing other coronaviruses that did not have the mutation.

The D614G mutation is thought to make the coronavirus more infectious, but it does not appear to make the disease more severe or help the virus escape vaccines.

The N501Y mutation arose independently in several variants of concern, including the B.1.1.7, B.1.351 and P.1 lineages.

The mutation is near the tip of the coronavirus spike, where it seems to change the shape of the protein to be a tighter fit with human cells.

The E484K mutation arose independently in multiple lineages, including B.1.351 and P.1. Scientists are also concerned that the mutation was recently found in some samples from the B.1.1.7 lineage from Britain. …
The mutation occurs near the top of the coronavirus spike, where it alters the shape of the protein. This change may help the spikes evade some types of coronavirus antibodies.

Covid mutation

January 30, 2021

b117 or b. mutation
D614G mutation

Evidence Builds That an Early Mutation Made the Pandemic Harder to Stop

Scientists were initially skeptical that a mutation made the coronavirus more contagious. But new research has changed many of their minds.


December 26, 2020

What to Know About the Covid Antibody Drugs That Could Help Many

Here’s information about who these therapies can help, how much they cost and how to find out if you can get them where you live.

Lilly’s neutralizing antibody bamlanivimab
Regeneron’s Casirivimab and Imdevimab Antibody Cocktail

pseudogenes/odorant receptors

December 17, 2020

Sequence Variants in TAAR5 & Other Loci Affect Human Odor Perception & Naming A variant in TAAR5 affects the perception of fish odor. Interesting to consider in relation to pseudogenization of the olfactory receptors

While about half of human odorant receptors are thought to be pseudogenes with loss-of-function, the Decode Genetics folks show that some sequence variants in odorant receptor genes are not

Covid mutation

November 30, 2020

D614G mutation

Evidence Builds That an Early Mutation Made the Pandemic Harder to Stop

Scientists were initially skeptical that a mutation made the coronavirus more contagious. But new research has changed many of their minds.

Dabbawala – Wikipedia

November 27, 2020

Eli Lilly’s Antibody Treatment Gets Emergency F.D.A. Approval – The New York Times

November 25, 2020 QT:{{”

The Food and Drug Administration has granted emergency authorization of a Covid-19 treatment made by the American pharmaceutical company Eli Lilly that was given to Chris Christie, the former New Jersey governor, when he was infected with the coronavirus.

The authorization, announced on Monday, applies only to people newly infected with the virus, and the agency said it should not be used in hospitalized patients. The treatment is approved for people 12 and older who have tested positive and are at risk for developing a severe form of Covid-19 or being hospitalized for the condition. That includes people who are over 65 and obese, the agency said — a key group that early studies have shown can benefit the most from the treatment.

Eli Lilly said that its treatment, called bamlanivimab, should be administered as soon as possible after a positive test, and within 10 days of developing symptoms.


Wearing a mask but not covering your nose? You’re doing it all wrong | The Star

October 3, 2020

anosmia & sniff tests

While it’s well established that the primary way people get infected with COVID-19 is from inhaling aerosol droplets, Kennedy said there is emerging evidence it’s “a lot easier” for the virus to get a grip on our internal system when it enters through the nasal passage versus the mouth.

That’s because the nasal passage tissue is rich in cells that have a certain receptor the virus attaches to.

“There’s more cells in the upper airway in the nasal passages that have high levels of receptor expression,” Kennedy explained. “So the virus is more likely to find the cell to infect, and it’s easier for the virus to infect cells sort of in the upper airway in the nasal passages than it is down in the lungs.”
It’s evident the nose and our sense of smell hold many answers to understanding COVID-19. It’s now clear a loss of sense of smell, known as anosmia, is one of the most common symptoms of COVID-19. Valentina Parma, chair of the Global Consortium for Chemosensory Research, said her organization’s data seems to show that anosmia is a better indicator of COVID-19 than fever.

For this reason, she’s an advocate of objective tests to measure sense of smell, such as sniff tests. To that end, her organization has developed an online smell and sniff test which can be completed by people by using scents in their own home, such as banana or shampoo. “}}

Moderna COVID-19 Vaccine Shows Immunogenicity in Older Patients

August 31, 2020

mRNA-1273 is their candidate