Archive for the 'SciLit' Category

Gencode De novo birth of functional microproteins in the human lineage: Cell Reports

December 21, 2022

https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01696-5

APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes | Nature

December 9, 2022

https://www.nature.com/articles/s41586-022-05439-w

Genetics goes to Hollywood | Nature Genetics

November 25, 2022

https://www.nature.com/articles/ng1197-260

https://www.nature.com/articles/ng1197-260.pdf?proof=t2019-8-23

Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution – ScienceDirect

November 25, 2022

https://www.sciencedirect.com/science/article/pii/S0092867422012582

https://twitter.com/ry_lister/status/1587101557010489344

Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution
Author links open overlay panelCharles A.Herring1210Rebecca
K.Simmons1210SaskiaFreytag1210DanielPoppe1210Joel
J.D.Moffet1JahnviPflueger12SamBuckberry12Dulce
B.Vargas-Landin12OlivierClément12Enrique GoñiEcheverría1Gavin J.Sutton3AlbaAlvarez-Franco4RuiHou1ChristianPflueger12KerrieMcDonald5Jose M.Polo67Alistair R.R.Forrest1Anna K.Nowak8…RyanLister1211

VOC(volatile organic compounds) in mask

November 20, 2022

Interesting article that implies one should “air out” a mask prior to wearing it (to get rid of toxic VOCs). For an N95, this requires 6 hrs.

Highly Time-Resolved and Nontargeted Characterization of Volatile Organic Compound Emissions from Face Masks

voc emission from a mask:
https://pubs.acs.org/doi/pdf/10.1021/acs.estlett.2c00524

Uncovering motif interactions from convolutional-attention networks for genomics

November 20, 2022

https://openreview.net/pdf?id=ITOQhccyRsk

An interesting work that improves the interpretability of TF binding predictors with minimal network design.

Deciphering eukaryotic gene-regulatory logic with 100 million random promoters

November 8, 2022

interesting – is there a dataset ?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954276/

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential hos t therapeutic targets | Nature Biotechnology

October 16, 2022

https://www.nature.com/articles/s41587-022-01474-0

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng & Haiyuan Yu

Deep learning guided optimization of human antibody against SARS-CoV-2 variants with broad neutralization

October 13, 2022

https://www.pnas.org/doi/10.1073/pnas.2122954119

Characteristics of Electric Scooter and Bicycle Injuries After Introduction of Electric Scooter Rentals in Oslo, Norway | Public Health | JAMA Network Open | JAMA Network

September 30, 2022

Emphasizes the dangers of unrestricted scooter use for pedestrians & the value of speed limits….
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2795144