Archive for the 'SciLit' Category

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

October 14, 2019

https://www.nature.com/articles/s41592-019-0575-8

Published: 07 October 2019

Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs

Tristan Bepler, Andrew Morin, Micah Rapp, Julia Brasch, Lawrence Shapiro, Alex J. Noble & Bonnie Berger

Nature Methods (2019)

High Time for Human Height

October 12, 2019

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269490/

Perit Dial Int. 2014 Nov-Dec; 34(7): 685–686.
doi: 10.3747/pdi.2014.00272
PMCID: PMC4269490
PMID: 25520478
Olivier Devuyst, Deputy Editor

Genome partitioning of genetic variation for height from 11,214 sibling pairs. – PubMed – NCBI

October 12, 2019

https://www.ncbi.nlm.nih.gov/pubmed/17924350

Am J Hum Genet. 2007 Nov;81(5):1104-10. Epub 2007 Oct 1.
Genome partitioning of genetic variation for height from 11,214 sibling pairs. Visscher PM1, Macgregor S, Benyamin B, Zhu G, Gordon S, Medland S, Hill WG, Hottenga JJ, Willemsen G, Boomsma DI, Liu YZ, Deng HW, Montgomery GW, Martin NG.

The Future of Genetic Studies of Complex Human Diseases | Science

October 12, 2019

https://science.sciencemag.org/content/273/5281/1516

Neil Risch, Kathleen Merikangas
proposed gwas

Complement Factor H Polymorphism in Age-Related Macular Degeneration | Science

October 12, 2019

https://science.sciencemag.org/content/308/5720/385.long

Robert J. Klein1, Caroline Zeiss2,*, Emily Y. Chew3,*, Jen-Yue Tsai4,*, Richard S. Sackler1, Chad Haynes1, Alice K. Henning5, John Paul SanGiovanni3, Shrikant M. Mane6, Susan T. Mayne7, Michael B. Bracken7, Frederick L. Ferris3, Jurg Ott1, Colin Barnstable2, Josephine Hoh7,†

see https://plu.mx/mtsinai/u/rklein

Complement Factor H Polymorphism in Age-Related Macular Degeneration

October 12, 2019

https://en.wikipedia.org/wiki/Factor_H

Complement Factor H Polymorphism in Age-Related Macular Degeneration

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1512523/

gene name Cfh

RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference: The American Journal of Human Genetics

October 8, 2019

https://www.cell.com/ajhg/fulltext/S0002-9297(13)00289-9#%20

Diabetes and RACE A Historical Perspective

October 5, 2019

ethnicity & diabetes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000712/

Biological composites—complex structures for functional diversity | Science

September 30, 2019

http://science.sciencemag.org/content/362/6414/543

QT:{{”
An example is the combination of rigidity and flexibility in protein-based teeth of the squid sucker ring. Other examples are time-delayed actuation in plant seed pods triggered by environmental signals, such as fire and water, and surface nanostructures that combine light manipulation with mechanical protection or water repellency. Bioinspired engineering transfers some of these structural principles into technically more relevant base materials to obtain new, often unexpected combinations of material properties. Less appreciated is the huge potential of using bioinspired structural complexity to avoid unnecessary chemical diversity, enabling easier recycling and, thus, a more sustainable materials economy.
“}}

DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing

September 30, 2019

DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392537/