https://journals.aps.org/prresearch/abstract/10.1103/PhysRevResearch.4.043013
Archive for the 'SciLit' Category
Lattice protein folding with QAnnealing
April 13, 2023Fast and accurate Bayesian polygenic risk modeling with variational inference: The American Journal of Human Genetics
April 13, 2023Quantitative GWAS & QTL studies
February 25, 2023Primer
Published: 25 January 2023
Molecular quantitative trait loci
François Aguet, Kaur Alasoo, Yang I. Li, Alexis Battle, Hae Kyung Im, Stephen B. Montgomery & Tuuli Lappalainen
Nature Reviews Methods Primers volume 3, Article number: 4 (2023)
Related to the discussion about quantitative GWAS and QTL, this primer review (and in particular box 1) is helpful in clarifying the (non) difference between the two types of studies:
https://www.nature.com/articles/s43586-022-00188-6
The statistics behind quantitative GWAS and QTL studies is the same, the only main difference might be the multiple testing correction procedure.
In general, it’s more a nomenclature distinction, as the term “QTL” is often used specifically for molecular traits.
BioGPT: generative pre-trained transformer for biomedical text generation and mining | Briefings in Bioinformatics | Oxford Academic
February 22, 2023Gencode De novo birth of functional microproteins in the human lineage: Cell Reports
December 21, 2022APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes | Nature
December 9, 2022Genetics goes to Hollywood | Nature Genetics
November 25, 2022Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution – ScienceDirect
November 25, 2022https://www.sciencedirect.com/science/article/pii/S0092867422012582
https://twitter.com/ry_lister/status/1587101557010489344
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution
Author links open overlay panelCharles A.Herring1210Rebecca
K.Simmons1210SaskiaFreytag1210DanielPoppe1210Joel
J.D.Moffet1JahnviPflueger12SamBuckberry12Dulce
B.Vargas-Landin12OlivierClément12Enrique GoñiEcheverría1Gavin J.Sutton3AlbaAlvarez-Franco4RuiHou1ChristianPflueger12KerrieMcDonald5Jose M.Polo67Alistair R.R.Forrest1Anna K.Nowak8…RyanLister1211
VOC(volatile organic compounds) in mask
November 20, 2022Interesting article that implies one should “air out” a mask prior to wearing it (to get rid of toxic VOCs). For an N95, this requires 6 hrs.
Highly Time-Resolved and Nontargeted Characterization of Volatile Organic Compound Emissions from Face Masks
voc emission from a mask:
https://pubs.acs.org/doi/pdf/10.1021/acs.estlett.2c00524
Uncovering motif interactions from convolutional-attention networks for genomics
November 20, 2022https://openreview.net/pdf?id=ITOQhccyRsk
An interesting work that improves the interpretability of TF binding predictors with minimal network design.
linkstream2 microblog 