Archive for the 'SciLit' Category

bioarxiv paper on Golden State Killer

February 2, 2019

https://www.biorxiv.org/content/10.1101/531384v1.abstract

The effects of death and post-mortem cold ischemia on human tissue transcriptomes | Nature Communications

February 2, 2019

Changes in gene activity may one day reveal…time of death
https://www.ScienceMag.org/news/2018/02/changes-gene-activity-may-one-day-reveal-time-death-crime-victims Discusses paper by @RodericGuigo (“Effects of death & post-mortem cold ischemia on….#transcriptomes,”
https://www.Nature.com/articles/s41467-017-02772-x). Obvious forensic interest but maybe a #privacy angle as well

Changes in gene activity may one day reveal the time of death for crime victims

Artificial intelligence turns brain activity into speech

January 23, 2019

https://www.sciencemag.org/news/2019/01/artificial-intelligence-turns-brain-activity-speech

Human genome-wide measurement of drug-responsive regulatory activity | Nature Communications

January 23, 2019

https://www.nature.com/articles/s41467-018-07607-x

Whole-genome STARR-seq

Human genome-wide measurement of drug-responsive regulatory activity Graham D. Johnson, Alejandro Barrera, Ian C. McDowell, Anthony M. D’Ippolito, William H. Majoros, Christopher M. Vockley, Xingyan Wang, Andrew S. Allen & Timothy E. Reddy
Nature Communications volume 9, Article number: 5317 (2018)

Accurate classification of BRCA1 variants with saturation genome editing. – PubMed – NCBI

January 23, 2019

https://www.ncbi.nlm.nih.gov/pubmed/30209399

Nature. 2018 Oct;562(7726):217-222. doi: 10.1038/s41586-018-0461-z. Epub 2018 Sep 12.
Accurate classification of BRCA1 variants with saturation genome editing. Findlay GM1, Daza RM1, Martin B1, Zhang MD1, Leith AP1, Gasperini M1, Janizek JD1, Huang X1, Starita LM2,3, Shendure J4,5,6.

Confounding: What it is and how to deal with it – ScienceDirect

January 13, 2019

https://www.sciencedirect.com/science/article/pii/S0085253815529748

Productivity and influence in bioinformatics: A bibliometric analysis using PubMed central

December 28, 2018

https://onlinelibrary.wiley.com/doi/full/10.1002/asi.22970
QT:{{”
Appendix shows the top 20 most highly cited authors based on 546,245 citations from PubMed Central. In all three periods, M. Gerstein, a professor in computational biology and bioinformatics at Yale University, is
both the most highly cited and productive author in the first author category.
“}}

Flexible statistical methods for estimating and testing effects in genomic studies with multiple conditions

December 25, 2018

seems to be better for eQTLs
https://www.nature.com/articles/s41588-018-0268-8

Genetic ancestry and the search for personalized genetic histories | Nature Reviews Genetics

November 19, 2018

https://www.nature.com/articles/nrg1405

A time to fast | Science

November 17, 2018

http://science.sciencemag.org/content/362/6416/770.full