Posts Tagged ‘#personalgenomics’

AstraZeneca launches project to sequence 2 million genomes

April 29, 2016

AstraZeneca…proj. to seq. 2M
http://www.nature.com/news/astrazeneca-launches-project-to-sequence-2-million-genomes-1.19797 Ironic @JCVenter Qt: Think carefully before you just dump your genome on the Internet

For complete irony, compare this qt w/ commentary on @JCVenter’s original personal
sequencehttp://www.WashingtonPost.com/wp-dyn/content/article/2007/09/06/AR2007090602362.htmlhttps://twitter.com/markgerstein/status/726064243695583232

QT:{{”
“Human Longevity’s databases are kept locked behind layers of security. “If I were advising a younger Craig Venter, I’d say, ‘Think carefully before you just dump your genome on the Internet’,” Venter says. “The levels of prediction are getting much more interesting.” “}}

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Genetic Testing May Be Coming to Your Office – WSJ

December 18, 2015

Genetic Testing May Be Coming to Your Office http://www.wsj.com/articles/genetic-testing-may-be-coming-to-your-office-1450227295 Insurance may monetize #PersonalGenomics as advertising did for the Web

‘Devious Defecator’ Case Tests Genetics Law

June 5, 2015

Devious Defecator Case Tests Genetics Law http://www.nytimes.com/2015/06/02/health/devious-defecator-case-tests-genetics-law.html Non-obvious outcome of GINA protects employees from non-medical DNA testing

genome_gov on Twitter: Video: Stanford U’s panel w/ Snyder & Nussbaum after screening of sci-fi film The Perfect 46. http://t.co/DguLkDuqWb #genetestethics

August 30, 2014

https://twitter.com/genome_gov/status/501439483116797954

‘A Troublesome Inheritance’ and ‘Inheritance’

August 10, 2014

‘A Troublesome Inheritance’ and ‘Inheritance’
http://www.nytimes.com/2014/07/13/books/review/a-troublesome-inheritance-and-inheritance.html

http://www.amazon.com/Inheritance-Genes-Change-Lives—Lives/dp/1455549444

available via audible

QT:{{”
One can find more productive ways to think about genes. As a physician who researches and treats rare genetic disorders, Sharon Moalem, the author of “Inheritance,” sees firsthand how sharply DNA can constrain our lives. Yet “our genes aren’t as fixed and rigid as most of us have been led to believe,” he says, for while genetic defects often create havoc, variable gene expression (our genes’ capacity to respond to the environment with a flexibility only now being fully recognized) can give our bodies and minds surprising resilience. In his new book, Moalem describes riveting dramas emerging from both defective genes and reparative epigenetics.
“}}

Phevor Combines Multiple Biomedical Ontologies for Accurate Identification of Disease-Causing Alleles in Single Individuals and Small Nuclear Families

May 9, 2014

http://www.cell.com/ajhg/abstract/S0002-9297(14)00112-8

The role of replicates for error mitigation in next-generation sequencing

December 16, 2013

http://www.nature.com/nrg/journal/vaop/ncurrent/full/nrg3655.html

on the various sources of errors in NGS and the role of replicates in reducing errors:

The Dizzying Journey to a New Cancer Arsenal

December 15, 2013

QT:{{”
So this is a therapy that goes by a somewhat unwieldy name of CAR T cell therapy….
So it’s sort of combining a few different types of
therapy; it’s the gene therapy, although the genetic modifications happen outside of the
person’s body, that’s one piece. It’s what’s called an immunotherapy, which means it’s
trying to kind of harness the immune system to fight cancer. And it’s also highly
personalized because every patient’s therapy is their own; you can’t just create T cells
and give them to everybody, it’s sort of a unique batch for each patient. “}}

Dizzying Journey to a New #Cancer Arsenal: CAR Tcell therapy combines gene therapy, immunotherapy & personalization into an effective treatment for ~$50K
http://www.sciencemag.org/content/340/6140/1514.summary

23andStupid: Is 23andMe Self-Destructing? – Forbes

December 6, 2013

23andStupid: Is #23andMe Self-Destructing? Amazing it hasn’t communicated with the FDA since May. http://onforb.es/1el3YsQ MT @matthewherper

Isp-fellows 23 & Me Take Down Notice

November 28, 2013

http://www.fda.gov/ICECI/EnforcementActions/WarningLetters/2013/ucm376296.htm

The Food and Drug Administration (FDA) is sending you this letter because you are marketing the 23andMe Saliva Collection Kit and Personal Genome Service (PGS) without marketing clearance or approval in violation of the Federal Food, Drug and Cosmetic Act (the FD&C Act)…..