Posts Tagged ‘quote’

Reddit and the Struggle to Detoxify the Internet

April 21, 2018

QT:{{”
Toward the end, the square was a dense, colorful tapestry, chaotic and strangely captivating. It was a collage of hundreds of incongruous images: logos of colleges, sports teams, bands, and video-game companies; a transcribed monologue from “Star Wars”; likenesses of He-Man, David Bowie, the “Mona Lisa,” and a former Prime Minister of Finland. In the final hours, shortly before the experiment ended and the image was frozen for posterity, BlackVoid launched a surprise attack on the American flag. A dark fissure tore at the bottom of the flag, then overtook the whole thing. For a few minutes, the center was engulfed in darkness. Then a broad coalition rallied to beat back the Void; the stars and stripes regained their form, and, in the end, the flag was still there.
“}}

Reddit & the Struggle to Detoxify the Internet
https://www.NewYorker.com/magazine/2018/03/19/reddit-and-the-struggle-to-detoxify-the-internet Describes an interesting expt: users compete & collaborate to determine the content of white square. “Toward the end, the square was…a collage…logos of colleges…teams… [&] likenesses of the Mona Lisa”

Need to make a molecule? Ask this AI for instructions

April 7, 2018

Need to make a molecule? Ask this AI for instructions
http://www.nature.com/articles/d41586-018-03977-w #DeepLearning to do better #retrosynthesis. Perhaps other things in chemistry could be learned as well!

QT:{{”
“The tool, described in Nature on 28 March1, is not the first software to wield artificial intelligence (AI) instead of human skill and intuition. Yet chemists hail the development as a milestone, saying that it could speed up the process of drug discovery and make organic chemistry more efficient.

“What we have seen here is that this kind of artificial intelligence can capture this expert knowledge,” says Pablo Carbonell, who designs synthesis-predicting tools at the University of Manchester, UK, and was not involved in the work. He describes the effort as “a landmark paper”.”
“}}

The Twin Astronaut’s DNA Really Did Change After a Year in Space—but Not in the Way You Think

April 7, 2018

The Twin Astronaut’s DNA Really Did Change After a Year in Space—but Not in the Way You Think
https://Slate.com/technology/2018/03/scott-kellys-dna-did-change-in-spacebut-not-the-way-you-think.html Interesting account of how #press accounts distort: Low oxygen changes in gene expression morph into actual DNA-level mutations

QT:{{”
“That’s not what researchers found. It is, however, what NASA’s own Jan. 31 news release initially implied. In the seventh paragraph of the garbly statement, the agency says that one of the “interesting” findings concerns what some call the “space gene.” The awkward paragraph then rushes from “the” space gene to saying that
“Researchers now know that 93% of Scott’s genes returned to normal after landing. However, the remaining 7% point to possible longer-term changes in genes related to his immune system” and some other processes.

Any reporter in a hurry to publish these fun twin findings from spaaaaace could easily have construed that to mean that some of Scott Kelly’s gene sequences literally changed. Except that the news release had already said a few paragraphs earlier that these changes were in gene expression, not the genes themselves. That means that the twins didn’t differ in their sequences but in how they used them. Space Kelly had changes in how his cells were using genes related to bone turnover, low oxygen, high carbon dioxide, and inflammation. These factors are all what you’d expect to change when you’re living in spaaaaace, where gravity doesn’t stress your bones sufficiently, oxygen isn’t as bountiful as on Earth, and you’re living in a tiny space where everyone’s exhaling carbon dioxide all the time. There are no surprises here.”
“}}

iPhone Notebook export for Patient H.M.: A Story of Memory, Madness, and Family Secrets

April 6, 2018

Notebook Export
Patient H.M.: A Story of Memory, Madness, and Family Secrets Dittrich, Luke
Citation (APA): Dittrich, L. (2016). Patient H.M.: A Story of Memory, Madness, and Family Secrets [Kindle iOS version]. Retrieved from Amazon.com

iPhone Notebook export for Nudge: Improving Decisions About Health, Wealth, and Happiness

March 31, 2018

Nudge: Improving Decisions About Health, Wealth, and Happiness
Thaler, Richard H.; Sunstein, Cass R.
Citation (APA): Thaler, R. H., & Sunstein, C. R. (2009). Nudge: Improving Decisions About Health, Wealth, and Happiness

Opinion | Stephen Hawking, Force of Nature

March 25, 2018

Stephen Hawking, Force of Nature
https://www.NYTimes.com/2018/03/14/opinion/stephen-hawking-death-.html Interesting obit, for a most noteable passing on #piday2018. How to learn from conversing with someone at 6 words per min.

QT:{{”
“Stephen could compose his sentences at a rate of only about six words a minute. At first I would sit impatiently, daydreaming on and off as I waited for him to finish his composition. But then one day I was looking over his shoulder at his computer screen, where the sentence he was constructing was visible, and I started thinking about his evolving reply. By the time he had completed it, I had had several minutes to ponder the ideas he was expressing.

This was a great help. It allowed me to more profoundly consider his remarks, and it enabled my own ideas, and my reactions to his, to percolate as they never could have in an ordinary conversation.” “}}

Opinion | The Latest Data Privacy Debacle

March 25, 2018

Latest Data Privacy Debacle, by @Zeynep
https://www.NYTimes.com/2018/01/30/opinion/strava-privacy.html Explains how #privacy is not solely an individual decision. Even well-informed consent is not sufficient protection. Great example of how aggregating @Strava use inadvertently compromised military base locations
QT:{{”
“If so, you probably checked a box to accept the app’s privacy policy. For most apps, the default setting is to share data with at least the company; for many apps the default is to share data with the public. But you probably didn’t even notice or care. After all, what do you have to hide?

For users of the exercise app Strava, the answer turns out to be a lot more than they realized. Since November, Strava has featured a global “heat map” showing where its users jogged or walked or otherwise traveled while the app was on. The map includes some three trillion GPS data points, covering more than 5 percent of the earth. Over the weekend, a number of security analysts showed that because many American military service members are Strava users, the map
inadvertently reveals the locations of military bases and the movements of their personnel.”
“}}

Opinion | The Latest Data Privacy Debacle
https://www.nytimes.com/2018/01/30/opinion/strava-privacy.html

Peter Breggin – Wikipedia

March 10, 2018

https://en.wikipedia.org/wiki/Peter_Breggin

QT:{{”
Peter Roger Breggin (born May 11, 1936)[1] is an American psychiatrist and critic of shock treatment and psychiatric medication. In his books, he advocates replacing psychiatry’s use of drugs and
electroconvulsive therapy with psychotherapy, education, empathy, love, and broader human services.[2]
“}}

New GWAS SCZ loci (nature genetics 2018)

March 5, 2018

Common #schizophrenia alleles are enriched in mutation-intolerant genes & in regions under strong background selection
https://www.nature.com/articles/s41588-018-0059-2 50 novel SCZ loci & 145 loci in total, from #GWAS – associated w/ 33 candidate causal genes

QT:{{”
We report a new genome-wide association study of schizophrenia (11,260 cases and 24,542 controls), and through meta-analysis with existing data we identify 50 novel associated loci and 145 loci in total. Through integrating genomic fine-mapping with brain expression and chromosome conformation data, we identify candidate causal genes within 33 loci.
“}}

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nature Genetics (2018)
doi:10.1038/s41588-018-0059-2

Suzanne Corkin, who studied the mind of a man with no memory, dies at 79 – The Washington Post

February 25, 2018

https://www.washingtonpost.com/national/health-science/suzanne-corkin-who-studied-the-mind-of-a-man-with-no-memory-dies-at-79/2016/06/04/010b267a-29ab-11e6-ae4a-3cdd5fe74204_story.html?utm_term=.4a05f1294a73
QT:{{"
In fact, they grew up a few miles apart, and Dr. Corkin lived on the same street as Scoville, the doctor who performed the operation on H.M. in 1953. Scoville later renounced experimental brain surgery and suggested H.M. as a possible research subject to Brenda Milner, a neuroscientist who became Dr. Corkin’s mentor at McGill.
"}}