Posts Tagged ‘cancer’

Invitae genetic testing

June 6, 2022


April 23, 2022

the marker paper of the Hartwig Medical Foundation paper.

Pan-cancer whole-genome analyses of metastatic solid tumours
Peter Priestley, Jonathan Baber, Martijn P. Lolkema, Neeltje Steeghs, Ewart de Bruijn, Charles Shale, Korneel Duyvesteyn, Susan Haidari, Arne van Hoeck, Wendy Onstenk, Paul Roepman, Mircea Voda, Haiko J. Bloemendal, Vivianne C. G. Tjan-Heijnen, Carla M. L. van Herpen, Mariette Labots, Petronella O. Witteveen, Egbert F. Smit, Stefan Sleijfer, Emile E. Voest & Edwin Cuppen
Nature volume 575, pages
210–216 (2019)

There have been numerous follow-up papers since.

Also, the Glioma Longitudinal Analysis (GLASS) Consortium datasets, which are publicly accessible via
The first marker paper is here:

uniformly processed and annotated tumor single-cell rna-seq data of > 2M cells

August 9, 2020

Cancer Genomics and Precision Medicine < Yale Cancer Center

June 2, 2020

Somatic evolution and global expansion of an ancient transmissible cancer lineage | Science

April 14, 2020

Adrian Baez-Ortega1, Kevin Gori1,*, Andrea Strakova1,*, Janice L. Allen2, Karen M. Allum3, Leontine Bansse-Issa4, …. Michael R. Stratton62, Ludmil B. Alexandrov63, Iñigo Martincorena62, Elizabeth P. Murchison1,†

Science 02 Aug 2019:
Vol. 365, Issue 6452, eaau9923
DOI: 10.1126/science.aau9923

Nongenic cancer-risk SNPs affect oncogenes, tumour-suppressor genes, and immune function

February 8, 2020

Tobacco smoking and somatic mutations in human bronchial epithelium

February 1, 2020

Tobacco smoking and somatic mutations in human bronchial epithelium

Kenichi Yoshida, Kate H. C. Gowers, Henry Lee-Six, Deepak P. Chandrasekharan, Tim Coorens, Elizabeth F. Maughan, Kathryn Beal, Andrew Menzies, Fraser R. Millar, Elizabeth Anderson, Sarah E. Clarke, Adam Pennycuick, Ricky M. Thakrar, Colin R. Butler, Nobuyuki Kakiuchi, Tomonori Hirano, Robert E. Hynds, Michael R. Stratton, Iñigo Martincorena, Sam M. Janes & Peter J. Campbell

Inherited determinants of early recurrent somatic mutations in prostate cancer | Nature Communications

December 29, 2019

Germline finding of a genetic variant that could be linked to SPOP mutations.

interesting perspective on cancer research in wsj + upcoming book

October 8, 2019

The focus is on improving detection vs. treatment of late stage disease.

Attached: Cancer Therapy Advisor Q&A

March 17, 2019

February 13, 2019
Q&A With Mark B. Gerstein, PhD, on Diagnostic Genomic vs Exomic Sequencing Bryant Furlow