Has one of cancer’s master switches been found?
Pancreatic cancer
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Posts Tagged ‘cancer’
A new drug targets one of cancer’s master switches
July 29, 2026Why Some Doctors Say There Are Cancers That Shouldn’t Be Treated – The New York Times
December 14, 2025The world is making impressive progress averting cancer
August 15, 2025https://www.economist.com/briefing/2025/07/17/the-world-is-making-impressive-progress-averting-cancer the war on cancer economist
Tumour evolution and microenvironment interactions in 2D and 3D space | Nature
November 10, 2024https://www.nature.com/articles/s41586-024-08087-4
Mo, C., Liu, J., Chen, S., Storrs, E., Da Costa, A. L. N. T., Houston, A., Wendl, M. C., Jayasinghe, R. G., Iglesia, M. D., Ma, C., Herndon, J. M., Southard-Smith, A. N., Liu, X., Mudd, J., Karpova, A., Shinkle, A., Goedegebuure, S. P., Abdelzaher, A. T. M. A., Bo, P., . . . Ding, L. (2024). Tumour evolution and microenvironment interactions in 2D and 3D space. Nature, 634(8036), 1178–1186.
https://doi.org/10.1038/s41586-024-08087-4
MET500
October 30, 2024useful for metastatic cancers
Hartwig
April 23, 2022the marker paper of the Hartwig Medical Foundation paper.
Pan-cancer whole-genome analyses of metastatic solid tumours https://www.nature.com/articles/s41586-019-1689-y
Peter Priestley, Jonathan Baber, Martijn P. Lolkema, Neeltje Steeghs, Ewart de Bruijn, Charles Shale, Korneel Duyvesteyn, Susan Haidari, Arne van Hoeck, Wendy Onstenk, Paul Roepman, Mircea Voda, Haiko J. Bloemendal, Vivianne C. G. Tjan-Heijnen, Carla M. L. van Herpen, Mariette Labots, Petronella O. Witteveen, Egbert F. Smit, Stefan Sleijfer, Emile E. Voest & Edwin Cuppen
Nature volume 575, pages
210–216 (2019)
There have been numerous follow-up papers since.
Also, the Glioma Longitudinal Analysis (GLASS) Consortium datasets, which are publicly accessible via www.synapse.org/glass.
The first marker paper is here:
https://www.nature.com/articles/s41586-019-1775-1.
Somatic evolution and global expansion of an ancient transmissible cancer lineage | Science
April 14, 2020Adrian Baez-Ortega1, Kevin Gori1,*, Andrea Strakova1,*, Janice L. Allen2, Karen M. Allum3, Leontine Bansse-Issa4, …. Michael R. Stratton62, Ludmil B. Alexandrov63, Iñigo Martincorena62, Elizabeth P. Murchison1,†
Science 02 Aug 2019:
Vol. 365, Issue 6452, eaau9923
DOI: 10.1126/science.aau9923
linkstream2 microblog 