Posts Tagged ‘to’

How to preserve secrets in a quantum age | The Economist

August 20, 2022

https://www.economist.com/science-and-technology/2022/07/13/how-to-preserve-secrets-in-a-quantum-age

Secondary_appt Great article on our faculty growth

August 3, 2022

https://seas.yale.edu/news-events/news/explosive-growth-faculty-courses-and-research-signal-new-era-computer-science-yale

How ‘Trustless’ Is Bitcoin, Really? – The New York Times

June 18, 2022

QT:{{”
Mark Gerstein, a professor of bioinformatics at Yale University, found in the research implications for data privacy. He recently stored a genome on a private blockchain, which allowed for a secure and tamperproof record. But he noted that in a public setting, as with Bitcoin’s blockchain, a data set’s size and subtle patterns made it susceptible to breaches, even as the data remained immutable. (Ms. Blackburn wasn’t tampering with the Bitcoin blockchain’s records.)

“That’s the amazing thing about big data,” Dr. Gerstein said. “If you have a big enough data set, it starts to leak information in unexpected ways.” Even more so when data from different sources are connected, he said: “When you combine one data set with another to make a bigger data set, nonobvious linkages can arise.”
“}}

https://www.nytimes.com/2022/06/06/science/bitcoin-nakamoto-blackburn-crypto.html

2022-06-08-09.34.24.NY-Times-story-on-bitcoin.x78qt.jpg
2022-06-08-09.36.23.NY-Times-story-on-bitcoin.x78qt.jpg

Somatic mutation rates scale with lifespan across mammals | Nature

April 22, 2022

https://www.nature.com/articles/s41586-022-04618-z

Mutation bias reflects natural selection in Arabidopsis thaliana | Nature

April 14, 2022

https://www.nature.com/articles/s41586-021-04269-6

https://twitter.com/MarkGerstein/status/1510065060806283269

Interesting paper, relating de novo mutation rate to epigenetic features. Wonder exactly how this connects to the fact that the background mutation rate in cancer genomes depends strongly on epigenetics.

Important genomic regions mutate less often than do other regions https://www.nature.com/articles/d41586-022-00017-6

Biologically informed deep neural network for prostate cancer discovery | Nature

April 12, 2022

https://www.nature.com/articles/s41586-021-03922-4

https://twitter.com/SEHanlon/status/1513548800949989377

At #AACR22, @VanAllenLab gives a nice overview of his paper using an interpretable NN model to get insights into determining cancer severity (https://nature.com/articles/s41586-021-03922-4)
Biologically informed deep neural network for prostate cancer discovery

Liked the way he hard-coded specific genes & pathways into the model & looked in detail where the model misclassified specific patients #AACR22 #AACR2022

Also, thought the hard-coding of genes into the model was similar to that in another interpretable AI approach (for brain disease, https://science.org/doi/10.1126/science.aat8464) Could have used the “rank projection trees” from this to highlight important genes #AACR22 #AACR2022

Kuramoto Model of Synchronization

March 23, 2022

the Kuramoto model of synchronization that could explain tissue level behavior from individual cells. Here is a nice YouTube video that explain this type of physical behavior with the Cornell professor in dynamic systems and chaos Steven Strogatz:

https://www.youtube.com/watch?v=t-_VPRCtiUg

This Price Surge Really Hits New Yorkers Hard – The New York Times

March 17, 2022

This Price Surge Really Hits New Yorkers Hard – The New York Times

https://www.nytimes.com/2022/03/07/nyregion/new-york-price-surge.html

Dr Kirstin Ferguson on Twitter: “The clever people at @NASA have created this deceptively simple yet highly effective data visualisation showing monthly global temperatures between 1880-2021. Watch until the end… Learn more here – https://t.co/yvLKEgcIZ7 #ClimateEmergency #ClimateCrisis #climate https://t.co/zkMrVgT9fq” / Twitter

March 17, 2022

https://twitter.com/kirstinferguson/status/1502801738193313798

Why world leaders are refusing to give Russia their DNA | The Week UK

March 6, 2022

https://www.theweek.co.uk/news/world-news/russia/955813/why-world-leaders-refuse-give-russia-dna

Thought this story was intriguing in relation to genomic #privacy & how the pandemic has potentially amplified worries about it. It was presaged by an opinion piece we did a decade ago
(https://USAToday.com/story/opinion/tory/opinion/2013/06/27/dov-greenbaum-and-mark-gerstein-on-nsa-and-genetics/2465589)

https://twitter.com/MarkGerstein/status/1500693248179904513