CATO score

May 28, 2017

Seq. variants influencing…TF occupancy Uses allelic analysis to develop the CATO score, how variants alter binding

This approach resulted in a simple scoring scheme, termed contextual analysis of transcription factor occupancy (CATO), that provides a recalibrated probability of affecting the binding of any transcription factor, as well as a quantitatively ranked list of transcription factor families whose binding might be altered.