Archive for the '–' Category

What Are ‘World Models’? The Key to the Next Big AI Leap – WSJ

January 2, 2026

What Are ‘World Models’? The Key to the Next Big AI Leap – WSJ https://www.wsj.com/tech/ai/world-models-ai-evolution-11275913
https://www.wsj.com/tech/ai/world-models-ai-evolution-11275913?mod=article_inline

1900: Rediscovery of Mendel’s Work

January 1, 2026

https://www.genome.gov/25520238/online-education-kit-1900-rediscovery-of-mendels-work QT:{{” DeVries, Correns and Tschermak independently rediscover Mendel’s work. Three botanists – Hugo DeVries, Carl Correns and Erich von Tschermak – independently rediscovered Mendel’s work in the same year, a generation after Mendel published his papers. They helped expand awareness of the Mendelian laws of inheritance in the scientific world.
The three Europeans, unknown to each other, were working on different plant hybrids when they each worked out the laws of inheritance. When they reviewed the literature before publishing their own results, they were startled to find Mendel’s old papers spelling out those laws in detail. Each man announced Mendel’s discoveries and his own work as confirmation of them. “}}

Asbjørn Følling and the discovery of phenylketonuria – PubMed

January 1, 2026

https://pubmed.ncbi.nlm.nih.gov/12785112/

Christ, S. E. (2003). Asbj�rn F�lling and the Discovery of
Phenylketonuria. Journal of the History of the Neurosciences, 12(1), 44–54. https://doi.org/10.1076/jhin.12.1.44.13788

The baby whose life was saved by the first personalized CRISPR therapy

January 1, 2026

https://www.nature.com/articles/d41586-025-03847-2#:~:text=CPS1%20deficiency%20compromises%20one%20of,deficiency%20die%20in%20early%20infancy. JK at UPenn

POSTER: ‘Human Knockout Project’ in a Pakistani Population with High Levels of Consanguinity – Mass General Advances in Motion

January 1, 2026

https://advances.massgeneral.org/cardiovascular/article.aspx?id=1014 QT:{{” “}}

Darwin Machines and the Nature of Knowledge – Henry Plotkin – Google Books

January 1, 2026

https://books.google.com/books/about/Darwin_Machines_and_the_Nature_of_Knowle.html?id=Q6vsdBdWkc8C QT:{{” Learn and survive. Behind this simple equation lies a revolution in the study of knowledge, which has left the halls of philosophy for the labs of science. This book offers a cogent account of what such a move does to our understanding of the nature of learning, rationality, and intelligence. Bringing together
evolutionary biology, psychology, and philosophy, Henry Plotkin presents a new science of knowledge, one that traces an unbreakable link between instinct and our ability to know. Contrary to the modern liberal idea that knowledge is something derived from experience, this science shows us that what we know is what our nature allows us to know, what our instincts tell us we must know. Since our ability to know our world depends primarily on what we call intelligence, intelligence must be understood as an extension of instinct. Drawing on contemporary evolutionary theory, especially notions of
hierarchical structure and universal Darwinism, Plotkin tells us that the capacity for knowledge, which is what makes us human, is deeply rooted in our biology “}}

Two Patients Declared ‘Cured’ of Leukemia a Decade After CAR T Cell Immunotherapy Infusion | University of Pennsylvania | Pathology and Laboratory Medicine

January 1, 2026

https://pathology.med.upenn.edu/news/two-patients-declared-cured-leukemia-decade-after-car-t-cell-immunotherapy-infusion#:~:text=A%20new%20analysis%20of%20the,Don%20Siegel%20and%20Bruce%20Levine.

what is car t therapy – Google Search

January 1, 2026

https://www.google.com/search?q=what+is+car+t+therapy&oq=what+is+CAR+T+ther&gs_lcrp=EgZjaHJvbWUqBwgAEAAYgAQyBwgAEAAYgAQyBggBEEUYOTIHCAIQABiABDIHCAMQABiABDIHCAQQABiABDIHCAUQABiABDIHCAYQABiABDIHCAcQABiABDIICAgQABgWGB4yCAgJEAAYFhge0gEIOTQ2MGowajeoAgCwAgA&sourceid=chrome&ie=UTF-8 QT:{{” CAR T-cell therapy (Chimeric Antigen Receptor T-cell therapy) is a personalized immunotherapy that genetically modifies a patient’s own T-cells (a type of white blood cell) in a lab to create
supercharged cancer-fighting cells, which are then infused back into the patient to find and destroy specific cancer cells, particularly effective for some blood cancers like leukemia and lymphoma that don’t respond to other treatments.
How it works:

T-cell Collection (Apheresis): Your T-cells are drawn from your blood, usually through a vein, and the rest of your blood is returned to you. Genetic Modification: In a specialized lab, a deactivated virus inserts new genes into your T-cells, creating Chimeric Antigen Receptors (CARs) on their surface, essentially turning them into “GPS-guided” missiles.
Expansion: These CAR T-cells multiply in the lab until there are millions of them.
Infusion: The lab-grown CAR T-cells are infused back into your body, often after a short course of chemotherapy to prepare you, where they hunt down and kill cancer cells.

“}}

A life-sciences job in Boston used to be a sure path to a high-paying career, but empty labs and unemployed grads now herald tougher times in the city

December 30, 2025

A life-sciences job in Boston used to be a sure path to a high-paying career, but empty labs and unemployed grads now herald tougher times in the city

https://www.wsj.com/tech/biotech/ph-d-s-cant-find-work-as-bostons-biotech-engine-sputters-729f0036?st=d1cKDJ&reflink=article_gmail_share

Streetwise: Markets were assailed by a trio of disruptive forces this year. Yet investors were rewarded for doing nothing 

December 29, 2025

Streetwise: Markets were assailed by a trio of disruptive forces this year. Yet investors were rewarded for doing nothing
https://www.wsj.com/finance/investing/in-a-wild-year-for-markets-investors-who-did-nothing-did-just-fine-721a9cc8?st=eU3cmm&reflink=article_gmail_share