Thought this gave a nice breakdown of the different effects
Why do women live longer than men?
https://ourworldindata.org/why-do-women-live-longer-than-men
Archive for the '–' Category
Men v women
December 31, 2024The Benefits of Intermittent Fasting – The New York Times
December 31, 2024QT:{{”
Most people trying to lose weight should strive for 16 calorie-free hours, he said, adding that “the easiest way to do this is to stop eating by 8 p.m., skip breakfast the next morning and then eat again at noon the next day.” (Caffeine-dependent people can have sugar- free black coffee or tea before lunch.) But don’t expect to see results immediately; it can take up to four weeks to notice an effect, he said.
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https://www.nytimes.com/2020/02/17/well/eat/the-benefits-of-intermittent-fasting.html
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December 31, 2024yuck….
Medreceiptforfk
December 31, 2024receipt for reimbursement
updateautopay947to400
December 31, 2024autopay things
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December 29, 2024For Her Scientist Husband, an Architect Creates a Boldly Contemporary Retreat
December 26, 2024A private study
QT:{{”
asked her to design a studio for him on their weekend property in upstate New York….studio, intended solely as his private refuge for reading, writing and thinking, she wanted the structure to be as open to its setting as possible. Located near a cliff above a large pond, it is surrounded by woodland and meadows.
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For Her Scientist Husband, an Architect Creates a Boldly Contemporary Retreat
Source: Architectural Digest
A Refuge in the Woods
Study reveals unique molecular machinery of woman who can’t feel pain | UCL News – UCL – University College London
December 26, 2024A World Without Pain | The New Yorker
December 26, 2024Levy, A. (2020, January 6). A world without pain. The New Yorker. https://www.newyorker.com/magazine/2020/01/13/a-world-without-pain
QT:{{”
“When I met Jo for the first time, I was just struck by her,” Cox, an affable forty-year-old with a scruffy beard, told me, one afternoon in his lab at U.C.L. …This imperviousness to pain is what makes her distinct from everyone else with a FAAH mutation. They, like even the most committed stoners, can still get hurt.
Cameron had the same FAAH mutation that many other people have—but there had to be something else at play. The scientists started their inquiry by isolating DNA from her blood, and then analyzing the protein-coding subset of her genome—the part that’s traditionally considered to be significant. “We didn’t really find anything,” Cox said. “So we decided, O.K., why don’t we look across the whole genome for bits that are deleted or duplicated? And, at the time, this new chip was just available, which enabled us to scan the whole genome and look for deletions”—snippets missing from her genetic code. “It was a lucky strike: we found that there was this deletion. But it was distinct from FAAH. It was away from FAAH, just downstream.”
The scientists noticed that the right edge of the deletion overlapped “a gene that was annotated as a pseudogene,” Cox said, and frowned. “Which is a term I don’t like.” A pseudogene is what’s been thought of as genetic detritus—a copy of a gene that’s just sitting there, not doing anything productive. One biochemist I spoke to likened a pseudogene to a rusted-out car you stumble on in the forest—only, in Cameron’s case, they put a key in the ignition and the car turned on. “To call it a pseudogene is misleading, because this is a gene that is expressed—it makes a product, a sequence in the DNA,” Cox said, with excitement. “It’s a real fascinating class of genes which have been severely overlooked in genetics until very recently.” Cox and his colleagues named this particular pseudogene—“It’s nicer to call it a gene,” he insisted—FAAH OUT. “It was a wordplay, really,” he said sheepishly. “The challenge now is to understand what it’s doing. Jo is the first person in the world that we know of with this.”
Cameron’s case is important in genetics, partly because it may supply evidence that pseudogenes are more significant than they were previously thought to be.
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