Biological Physics: Energy, Information, Life – Good intuition for free energy as max laziness & max sloppiness!
http://www.math.colostate.edu/~yzhou/course/math676_spring2013/biophys_Nelson.pdf
Archive for the 'SciLit' Category
www.math.colostate.edu/~yzhou/course/math676_spring2013/biophys_Nelson.pdf
July 6, 2013First functional human organ generated from pluripotent stem cells
July 6, 2013Vascularized and functional human liver from an iPSC-derived organ bud transplant
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12271.html
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci : Nature Genetics : Nature Publishing Group
July 5, 2013Hinds et al. from 23andme
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2686.html
Genome Biology | Full text | Hypothesis-driven genomics pays off
July 1, 2013QT:
Despite its financial woes, deCode has begun to pay off, not in money, but in science. About 10 years ago its scientists co-discovered the association of the neuroregulin 1 (NRG1) gene with schizophrenia, and they have had some more modest successes with other diseases. But last week, deCode produced not only its most important genetic finding to date, but also quite possibly the most important genetic finding in Alzheimer’s disease in the last 20 years.
To be fair, the company had plenty of help. Coauthors of their paper, “A mutation in APP protects against Alzheimer’s disease and
age-related cognitive decline” … the key to the study rests on two things: the use of genetically defined populations, and genome sequencing and analysis based on a specific hypothesis.
”
http://genomebiology.com/2012/13/10/176
Nice overview of #Alzheimer’s research giving context for deCode’s finding of a protective APP mutation
http://genomebiology.com/2012/13/10/176
Genome Biology | Full text | In praise of model organisms
July 1, 2013QT:
Despite numerous examples of the enormous value of model organism research, many scientists and scientific administrators seem to think that nothing lower than a mouse is suitable for cutting-edge biology anymore.
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http://genomebiology.com/2011/12/5/115
best figures ever! =)
June 29, 2013Hand drawn figures in PubMed central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261217/
not actually not that much worse than those in the final MS:
Extensive Gene Traffic on the Mammalian X Chromosome
June 29, 2013Paper Integrative analysis of C. elegans modENCODE ChIP-seq data sets to infer gene regulatory interactions
June 29, 2013Genome Research
http://genome.cshlp.org/content/23/6/941.full?rss=1
Appears to use much of the existing modencode data
linkstream2 microblog 