Archive for the 'SciLit' Category
A War on Obesity, Not the Obese
March 3, 2013Comment on “Evidence of Abundant and Purifying Selection in Humans for Recently Acquired Regulatory Functions ”
March 2, 2013The Vast, Conserved Mammalian lincRNome
March 2, 2013paper comparing human and mouse lncRNAs
The Vast, Conserved Mammalian lincRNome
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002917
regulatory cancer drivers
March 1, 2013Two papers in Science talking about recurrent mutations in TERT promoter in melanoma.
1) http://www.sciencemag.org/content/339/6122/957.full
Highly Recurrent TERT Promoter Mutations in Human Melanoma
Franklin W. Huang1,2,3,* Eran Hodis1,3,4,*,Mary Jue Xu1,3,4,Gregory V. Kryukov1,Lynda Chin5,6,Levi A. Garraway1,2,3,†
2) http://www.sciencemag.org/content/339/6122/959.full
TERT Promoter Mutations in Familial and Sporadic Melanoma
Susanne Horn1,2,Adina Figl1,2,P. Sivaramakrishna Rachakonda1,Christine Fischer3,Antje Sucker2,Andreas Gast1,2,Stephanie Kadel1,2,Iris Moll2,Eduardo Nagore4,Kari Hemminki1,5,Dirk Schadendorf2,*,†,Rajiv Kumar1,*,†
FST and QST Under Neutrality – Genetics
March 1, 2013circRNAs can be functionally important
February 28, 2013Old idea or miRNS sponging applied to a new class of RNAs — circRNAs
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11993.html?WT.ec_id=NATURE-20130228
Predicting the Binding Patterns of Hub Proteins: A Study Using Yeast Protein Interaction Networks
February 24, 2013used the singlish/multi concept. Then used machine learning to predict whether a protein is singlish or multi
PLOS ONE
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0056833
Taner Z. Sen
Developmental Milestones Punctuate Gene Expression in the Caenorhabditis Embryo
February 19, 2013http://www.cell.com/developmental-cell/abstract/S1534-5807%2812%2900142-6
Michal Levin, Tamar Hashimshony, Florian Wagner, and Itai Yanai.
Developmental milestones punctuate gene expression in the
Caenorhabditis embryo. Developmental Cell (May 2012)
Nice disussion of the phylotypic stage .
Figure 4S-E have stage mapping between dmel and celegans
Abstractions for genomics – how data processing can be layered, including separating evidence from interference
February 17, 2013Abstractions for genomics
Communications of the ACM
Volume 56 Issue 1, January 2013
Pages 83-93
http://cseweb.ucsd.edu/~varghese/PAPERS/querythegenome.pdf
http://dl.acm.org/citation.cfm?id=2398376
PLOS Computational Biology: Large-Scale Trends in the Evolution of Gene Structures within 11 Animal Genomes
February 16, 2013intron & exon length distributions
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.0020015
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