Archive for the 'SciLit' Category

About bread wheat genome

December 17, 2012

QT:”
Bread wheat (Triticum aestivum) is a globally important crop, accounting for 20 per cent of the calories consumed by humans….Here we report the sequencing of its large, 17-gigabase-pair, hexaploid genome using 454 pyrosequencing, and comparison of this with the sequences of diploid ancestral and progenitor genomes. We identified between 94,000 and 96,000 genes.
”
http://www.nature.com/nature/journal/v491/n7426/full/nature11650.html?WT.ec_id=NATURE-20121129

Epigenetic priors for identifying active tran… Bioinformatics. 2012 – PubMed – NCBI

December 16, 2012

Bioinformatics. 2012 Jan 1;28(1):56-62. doi:
10.1093/bioinformatics/btr614. Epub 2011 Nov 8.
Epigenetic priors for identifying active transcription factor binding sites. Cuellar-Partida G, Buske FA, McLeay RC, Whitington T, Noble WS, Bailey TL.

Score (posterior, at position i in the genome) = PWM for TF t at position i + priors at i (H3K4me + Dnase), gets 60% sens. at FPR of 1% averaged over all i & t, using essentially equal weighting on each functional genomics track. One issue here is because of the huge size of the genome the 1% FPR actually turns into a very low PPV, giving 5 FPs for each TP in practice.
http://www.ncbi.nlm.nih.gov/pubmed/22072382

CiteSeerX — Aide-Memoire. High-Dimensional Data Analysis: The Curses and Blessings of Dimensionality

December 6, 2012

http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.164.6687

The Benefits of Being Economics Professor A (and not Z)

December 6, 2012

http://ideas.repec.org/p/ces/ceswps/_1948.html

Long noncoding RNAs in C. elegans

December 5, 2012

http://genome.cshlp.org/content/22/12/2529.full

Differential Relationship of DNA Replication Timing to Different Forms of Hu…

December 1, 2012

http://www.ncbi.nlm.nih.gov/PubMed/23176822Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation.
by Koren A, Polak P, Nemesh J, Michaelson JJ, Sebat J, Sunyaev SR, McCarroll SA on 11/28/12

Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation.
Am J Hum Genet. 2012 Nov 20

Article: Predicting cancer drivers: are we there yet?

December 1, 2012

http://genomemedicine.com/content/4/11/88

associated with transFIC method

Non-coding variation review

November 25, 2012

http://www.nature.com/nbt/journal/v30/n11/full/nbt.2422.html

Voronoia4RNA–a database of atomic packing densities of RNA structures and their complexes

November 25, 2012

http://www.ncbi.nlm.nih.gov/pubmed/23161674

Analysis of ~1900 RNA containing structures v ~50 non-redundant ones in http://papers.gersteinlab.org/papers/nucprot

Why rodent pseudogenes refuse to retire

November 23, 2012

http://genomebiology.com/2012/13/11/178