Archive for the 'SciLit' Category
The pathologies of big data
June 24, 2012Big data: science in the petabyte era : Nature
June 24, 2012The Universe Online
June 24, 2012http://www.sciencemag.org/content/329/5995/1028.long
some bits on astro big data
Communication and Data-Intensive Science in the Beginning of the 21st Century | Abstract
June 24, 2012primate OR pseudogene links
June 22, 2012links to the correction/retraction of the Gilad et al. paper on primate olfactory receptors:
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0050148
Matsui et al. paper looking at genome-wide ORs:
http://mbe.oxfordjournals.org/content/27/5/1192.short
epigenomics data resource guide
June 22, 2012The Epigenomics common fund project just published a guide to their project, describing the data and how to access the data.
Epigenomics. 2012 Jun;4(3):317-24.
The NIH Roadmap Epigenomics Program data resource.
Chadwick LH.
PMID:22690667
http://www.ncbi.nlm.nih.gov/pubmed/22690667
Genome Research Long non-coding RNAs in C. elegans by Jin-Wu Nam and David Bartel
June 22, 2012http://genome.cshlp.org/content/early/2012/06/15/gr.140475.112.abstract?papetoc
QT:”
We found hundreds of long intervening ncRNAs (lincRNAs), which had single- or multi-exonic structures that did not overlap protein-coding transcripts, and about seventy antisense lncRNAs (ancRNAs), which were complementary to protein-coding transcripts.
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Reference “A large-scale method to measure absolute protein p…”
June 10, 2012Nat. Methods. 2011 Aug; vol. 8(8) pp. 677-83
A large-scale method to measure absolute protein phosphorylation stoichiometries.
Wu R, Haas W, Dephoure N, Huttlin EL, Zhai B, Sowa ME, Gygi SP URL – http://www.ncbi.nlm.nih.gov/pubmed/21725298?dopt=Citation
Q: how does phosphorylation stoichiometry relate to the phosphorylome ? how many of the things are fully phosphorylated ?
A tissue-specific atlas of mouse protein phosphorylatio… Cell. 2010 – PubMed – NCBI
June 10, 2012http://www.ncbi.nlm.nih.gov/pubmed/21183079
A tissue-specific atlas of mouse protein phosphorylation and expression
interesting to intersect with mouse encode in relation to TFs & gene expression – how does it relate to cell lines ?
linkstream2 microblog 