Archive for the 'SciLit' Category

PLOS Genetics: Genetic Adaptation Associated with Genome-Doubling in Autotetraploid Arabidopsis arenosa

May 9, 2015

PLOS Genetics: Genetic Adaptation Associated with Genome-Doubling in Autotetraploid Arabidopsis arenosa
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003093

Advantages and pitfalls in the application of mixed-model association methods : Nature Genetics : Nature Publishing Group

May 9, 2015

Advantages and pitfalls in the application of mixed-model association methods : Nature Genetics : Nature Publishing Group
http://www.nature.com/ng/journal/v46/n2/abs/ng.2876.html

BMC Genomics | Abstract | Assessing structural variation in a personal genome—towards a human reference d iploid genome

May 4, 2015

consensus method

http://www.biomedcentral.com/1471-2164/16/286/abstract

Genome Biology | Full text | An integrative probabilistic model for identification of structural variation in sequencing data

May 4, 2015

QT:{{”
We introduce GASVPro, an algorithm combining both paired read and read depth signals into a probabilistic model that can analyze multiple alignments of reads.
“}}

http://genomebiology.com/2012/13/3/R22

Characterization of structural variants with single molecule and hybrid sequencing approaches

May 4, 2015

QT:{{”
We present MultiBreak-SV, an algorithm to detect structural variants (SVs) from single molecule sequencing data, paired read sequencing data, or a combination of sequencing data from different platforms. “}}

uses pacbio

http://bioinformatics.oxfordjournals.org/content/30/24/3458.long

Longitudinal analysis of microbial interaction between humans and the indoor environment

May 3, 2015

Microbial interaction betw humans & the indoor environment http://www.sciencemag.org/content/345/6200/1048.abstract
Unique personal signatures w/ implications for #forensics

Places change to conform to signature…..

The evolutionary history of lethal metastatic prostate cancer : Nature : Nature Publishing Group

May 2, 2015

The evolutionary history of…metastatic prostate #cancer http://www.nature.com/nature/journal/vaop/ncurrent/full/nature14347.html Unexpected: polyclonal "seeding" w/ much met-to-met spread

Reverse-engineering censorship in China: Randomized experimentation and participant observation

May 2, 2015

Reverse-engineering #censorship in #China: Randomized expts
http://www.sciencemag.org/content/345/6199/1251722.abstract Criticism is ok but calls for collective action are not

Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

May 2, 2015

Transmissible Dog #Cancer #Genome Reveals…History of…Cell Lineage http://www.sciencemag.org/content/343/6169/437.abstract 1.9M somatic mutations from origin ~11K yrs ago

Can disparities be deadly?

April 28, 2015

Can disparities be deadly? http://www.sciencemag.org/content/344/6186/829.summary
Correlation v causation: does high government rank lead to good health or the converse

For the famous Whitehall study

http://www.sciencemag.org/content/344/6186/829.summary