http://genome.cshlp.org/content/early/2013/11/05/gr.164806.113.abstract Interesting association of viral integration, relevant to bkpts
Archive for the 'SciLit' Category
HPV integration and SVs
November 10, 2013Genomically Recoded Organisms Expand Biological Functions
November 5, 2013#Genomically Recoded Organisms Expand Biological Functions: Changing UAG from stop to a new amino acid in E. coli http://www.sciencemag.org/content/342/6156/357.abstract
Marc J. Lajoie1,2,
Alexis J. Rovner3,4,
Daniel B. Goodman1,5,
Hans-Rudolf Aerni4,6,
Adrian D. Haimovich3,4,
Gleb Kuznetsov1,
Jaron A. Mercer7,
Harris H. Wang8,
Peter A. Carr9,
Joshua A. Mosberg1,2,
Nadin Rohland1,
Peter G. Schultz10,
Joseph M. Jacobson11,12,
Jesse Rinehart4,6,
George M. Church1,13,*,
Farren J. Isaacs3,4,*
Pheromonal Induction of Spatial Learning in Mice
November 1, 2013Interesting discussion of a protein produced in mice and dog urine that acts as a pheromone. It is called Darcin and was named after the famous character, Mr. Darcy from Jane Austen’s novels, since it makes females very attracted to males.
Pheromonal Induction of Spatial Learning in Mice: Darcin
(#Austen-inspired name) acts as an attractant to females
https://www.sciencemag.org/content/338/6113/1462
How Big Is the Proton?
October 31, 2013Interesting discussion of a sort of aberrant hydrogen atom that has a proton and a muon as opposed to an electron. Since the muon is much heavier than the electron it sits much closer to the proton giving a sense of its shape. One can only imagine what muonic helium would look like with two of these things.
How Big Is the Proton? As determined from muonic hydrogen
http://www.sciencemag.org/content/339/6118/405.summary #physics
Medical research: Cell division : Nature News & Comment
October 30, 2013Cell division
.@NatureNews on WI-38, a cell line w/ tricky ethics (like #HeLa), from an aborted fetus, but essential for vaccines
http://www.nature.com/news/medical-research-cell-division-1.13273
Interesting discussion of another cell line other than Hela called WI-38 that has some challenging ethical issues. This cell line was taken from a fetus and used to develop important viral medications. The person who originally did this — Hayflick — identified four stakeholders that should really be compensated: the estate of the unborn child, the scientists, the institution and the funders.
In 1962, Leonard Hayflick created a cell strain from an aborted fetus. More than 50 years later, WI-38 remains a crucial, but controversial, source of cells.
http://www.nature.com/news/medical-research-cell-division-1.13273
Temporal cloak erases data from history : Nature News & Comment
October 24, 2013Interesting discussion of a temporal cloaking device that can hide picosecond timescales. This could potentially be used to obscure communication between two parties — from say the CIA — in a short time period.
Temporal cloak erases data from history. Perhaps useful to foil future #NSA metadata collection.
http://www.nature.com/news/temporal-cloak-erases-data-from-history-1.13141 #privacy
http://www.nature.com/news/temporal-cloak-erases-data-from-history-1.13141
Genome Biology | Full text | Astrogenomics: big data, old problems, old solutions?
October 22, 2013MT @genomematt Astrogenomics: #bigdata, old problems, old solutions: Both propose organizing the data hierarchically
http://genomebiology.com/2013/14/8/129
Metallurgy: Iron production electrified : Nature : Nature Publishing Group
October 20, 2013Iron production electrified. New tech for extraction of Fe directly from its oxide w/o C via high-T #electrolysis.
http://www.nature.com/nature/journal/v497/n7449/full/nature12102.html
This piece contains an interesting discussion of new blast furnace technology, which enables one to extract the oxygen directly from iron oxide without the need for carbon or the creation of carbon dioxide as it uses electrolysis. The key idea is being able to do this at very high temperatures.
QT:”
Kerri Smith: Extracting iron from its naturally found form, iron oxide is a hot and heavy business. You throw your iron oxide and some carbon into a blastfurnace and then heat it to 1600 degrees Celsius, out comes iron, worldwide about a billion tons of it a year, but also outcomes carbon dioxide- bad news for the environment. Scientists would like to use other friendlier methods to make iron. This week a team from MIT reports a way to convert iron oxide to iron using electricity. It’s not a new idea. It’s basically a form of
electrolysis which extracts the oxygen leaving pure iron behind. But they’ve gotten over the biggest problem, finding material that can withstand the temperatures of molten metal oxides. Metallurgist Derek Fray at the University of Cambridge in the UK has written a News and Views article about the research. He started by telling me how much CO2, iron production is responsible for. Nature (2013); Nature(2013) ”
http://www.nature.com/nature/journal/v497/n7449/full/nature12102.html
Anatomy of successful computational biology software
October 18, 2013Anatomy of successful #compbio software: Right place at right time, Packages, Clean design, Insight.. go.nature.com/aUCA5y MT @BetaScience The anatomy of successful computational biology software
http://www.nature.com/nbt/journal/v31/n10/full/nbt.2721.html
PLOS ONE: Content Disputes in Wikipedia Reflect Geopolitical Instability
October 17, 2013Content Disputes in #Wikipedia Reflect Geopolitical Instability: bio #network ideas applied to social context
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0020902
Content Disputes in Wikipedia Reflect Geopolitical Instability http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0020902
(guilt-by-association)
linkstream2 microblog 