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September 4, 2023astrocyte
QT:{{”
Autism is one. In 2017 Ishizuka Kanako of the Nagoya Institute of Technology, in Japan, found a link between an increased risk of autism and the presence of a pair of genetic variants known to disrupt, in microglia, the expression of a protein called cx3cr1. And in 2020 Xu Zhixiang of Scripps Research, in San Diego, showed a range of microglial protein-synthesis problems cause autism-like symptoms in mice.
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Many researchers now talk of “tripartite” synapses as being standard in the brain. Their transistor-like three-element composition has one part (the astrocyte) which acts like a transistor’s “base” connection, regulating the passage of signals between the other two (the neurons, the equivalents of a transistor’s “emitter” and “collector”). Since transistors form the logic gates of computers, that is intriguing. “}}
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