https://www.sciencedirect.com/science/article/pii/S009286741830374X
DNA is not our destiny; it’s just a very useful tool | Ewan Birney | Science | The Guardian
April 7, 2018Opinion | The Secret to a Longer Life? Don’t Ask These Dead Longevity Researchers
April 7, 2018The Secret to a Longer Life? Don’t Ask These Dead #Longevity Researchers, by @PaganKennedy
https://www.NYTimes.com/2018/03/09/opinion/sunday/longevity-pritikin-atkins.html Amazing how early many of the fad diet & #exercise gurus passed away. A contrast w/ the robust lifespan gains from public-health & environmental measures
[tagd longevity,aging,exercise,health,excerptedquote,x57s]
QT:{{”
“That’s the problem with n-of-one-ism, in which we pursue,
individually and alone, our own path to health. The greatest gains in longevity have occurred not because of personal choices but because of public sanitation, clean water and the control of infectious diseases. According to Dr. Thomas Frieden, the former director of the Centers for Disease Control and Prevention, “since 1900, the average life span in the United States has increased by more than 30 years; 25 years of this gain have been attributed to public health advances.”
…
The founder of Bulletproof Coffee recently bragged that he hopes to live to age 180, in part by sipping one of his company’s signature drinks made with “Brain Octane Oil.” But aging isn’t some kind of competitive sport you play against your peers. When it comes to staying alive, we’re all in it together.
“}}
Need to make a molecule? Ask this AI for instructions
April 7, 2018Need to make a molecule? Ask this AI for instructions
http://www.nature.com/articles/d41586-018-03977-w #DeepLearning to do better #retrosynthesis. Perhaps other things in chemistry could be learned as well!
QT:{{”
“The tool, described in Nature on 28 March1, is not the first software to wield artificial intelligence (AI) instead of human skill and intuition. Yet chemists hail the development as a milestone, saying that it could speed up the process of drug discovery and make organic chemistry more efficient.
“What we have seen here is that this kind of artificial intelligence can capture this expert knowledge,” says Pablo Carbonell, who designs synthesis-predicting tools at the University of Manchester, UK, and was not involved in the work. He describes the effort as “a landmark paper”.”
“}}
The Twin Astronaut’s DNA Really Did Change After a Year in Space—but Not in the Way You Think
April 7, 2018The Twin Astronaut’s DNA Really Did Change After a Year in Space—but Not in the Way You Think
https://Slate.com/technology/2018/03/scott-kellys-dna-did-change-in-spacebut-not-the-way-you-think.html Interesting account of how #press accounts distort: Low oxygen changes in gene expression morph into actual DNA-level mutations
QT:{{”
“That’s not what researchers found. It is, however, what NASA’s own Jan. 31 news release initially implied. In the seventh paragraph of the garbly statement, the agency says that one of the “interesting” findings concerns what some call the “space gene.” The awkward paragraph then rushes from “the” space gene to saying that
“Researchers now know that 93% of Scott’s genes returned to normal after landing. However, the remaining 7% point to possible longer-term changes in genes related to his immune system” and some other processes.
Any reporter in a hurry to publish these fun twin findings from spaaaaace could easily have construed that to mean that some of Scott Kelly’s gene sequences literally changed. Except that the news release had already said a few paragraphs earlier that these changes were in gene expression, not the genes themselves. That means that the twins didn’t differ in their sequences but in how they used them. Space Kelly had changes in how his cells were using genes related to bone turnover, low oxygen, high carbon dioxide, and inflammation. These factors are all what you’d expect to change when you’re living in spaaaaace, where gravity doesn’t stress your bones sufficiently, oxygen isn’t as bountiful as on Earth, and you’re living in a tiny space where everyone’s exhaling carbon dioxide all the time. There are no surprises here.”
“}}
iPhone Notebook export for Patient H.M.: A Story of Memory, Madness, and Family Secrets
April 6, 2018Notebook Export
Patient H.M.: A Story of Memory, Madness, and Family Secrets Dittrich, Luke
Citation (APA): Dittrich, L. (2016). Patient H.M.: A Story of Memory, Madness, and Family Secrets [Kindle iOS version]. Retrieved from Amazon.com
IMPC | International Mouse Phenotyping Consortium
April 6, 2018IMPC | International Mouse Phenotyping Consortium
http://www.mousephenotype.org/
