Posts Tagged ‘AD’

Nature medcine “A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s dis ease pathology”

January 26, 2026

QT:{{”
The DROP-AD project investigates the potential of dried plasma spot (DPS) and dried blood spot (DBS) analysis, derived from capillary blood, for detecting AD biomarkers, including phosphorylated tau at amino acid 217 (p-tau217), glial fibrillary acidic protein and neurofilament light. …. Similarly, we demonstrated the successful detection of glial fibrillary acidic protein and neurofilament light with strong correlations between DBS and DPS, respectively, using paired venous plasma samples.
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Might find this paper very interesting. Just published this month in Nature Medicine. “A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology.”

A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology – Nature Medicine
https://www.nature.com/articles/s41591-025-04080-0

Frontotemporal dementia – Wikipedia

May 18, 2025

https://en.wikipedia.org/wiki/Frontotemporal_dementia

Pick’s disease

Type 3 Diabetes and Its Role Implications in Alzheimer’s Disease – PMC

February 24, 2025

https://pmc.ncbi.nlm.nih.gov/articles/PMC7246646/

Opinion | The Long Shadow of Fraud in Alzheimer’s Research – The New York Times

February 1, 2025

https://www.nytimes.com/2025/01/24/opinion/alzheimers-fraud-cure.html

How a new kind of vaccine could lead to the eradication of Alzheimer’s and dementia | New Scientist

November 10, 2024

https://www.newscientist.com/article/mg26335060-900-how-a-new-kind-of-vaccine-could-lead-to-the-eradication-of-alzheimers/

Single-cell multiregion dissection of Alzheimer’s disease | Nature

July 24, 2024

https://www.nature.com/articles/s41586-024-07606-7

Has Alzheimer’s met its match? – ScienceDirect

February 29, 2024

https://www.sciencedirect.com/science/article/abs/pii/S0262407923009429?via%3Dihub

New Scientist
Volume 258, Issue 3440, 27 May 2023, Pages 14-15
Has Alzheimer’s met its match?
Clare Wilson

Conquering Alzheimer’s: a look at the therapies of the future

May 29, 2023

https://www.nature.com/articles/d41586-023-00954-w

lecanemab is one of the new drugs

Cholesterol and dementia | Alzheimer’s Society

May 12, 2023

https://www.alzheimers.org.uk/about-dementia/risk-factors-and-prevention/cholesterol-and-dementia

QT:{{”
A meta-analysis is a study that looks at lots of previous studies and analyses all of the data together to increase the number of people studied and to look at the information in a consistent way. A meta-analysis looking at observational studies investigating statins and the risk of dementia looked at data from 11 studies, involving over 23,000 participants, who had been taking statins for between 3 and nearly 25 years on average. When all of the data was analysed together, the researchers found that those people taking statins had a 29 per cent reduced risk of developing dementia.
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Could drugs prevent Alzheimer’s? These trials aim to find out

March 22, 2022

https://www.nature.com/articles/d41586-022-00651-0
taking gantenerumab