Posts Tagged ‘future0mg’

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Creation of a bacterial cell controlled by a chemically synthesized genome – PubMed

December 23, 2025

https://pubmed.ncbi.nlm.nih.gov/20488990/

Gibson, D. G., Glass, J. I., Lartigue, C., Noskov, V. N., Chuang, R., Algire, M. A., Benders, G. A., Montague, M. G., Ma, L., Moodie, M. M., Merryman, C., Vashee, S., Krishnakumar, R., Assad-Garcia, N., Andrews-Pfannkoch, C., Denisova, E. A., Young, L., Qi, Z.,
Segall-Shapiro, T. H., . . . Venter, J. C. (2010). Creation of a bacterial cell controlled by a chemically synthesized genome. Science, 329(5987), 52–56. https://doi.org/10.1126/science.1190719

booting up a synthetic genome JCVI-syn1.0

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Har Gobind Khorana – Wikipedia

December 22, 2025

https://en.wikipedia.org/wiki/Har_Gobind_Khorana

QT:{{”

During his tenure at this university, he completed the work that led to sharing the Nobel Prize in 1968. The Nobel web site states that it was “for their interpretation of the genetic code and its function in protein synthesis”. Har Gobind Khorana’s role is stated as follows: he “made important contributions to this field by building different RNA chains with the help of enzymes. Using these enzymes, he was able to produce proteins. ….

Their Nobel lecture was delivered on 12 December 1968.[24] Khorana was the first scientist to chemically synthesize oligonucleotides.[25] This achievement, in the 1970s, was also the world’s first synthetic gene; in later years, the process has become widespread.[22] Subsequent scientists referred to his research while advancing genome editing with the CRISPR/Cas9 system.[21]

After years of work, he was the first in the world to complete the total synthesis of a functional gene outside a living organism in 1972.[10] He did this by extending the above to long DNA polymers using non-aqueous chemistry and assembled these into the first synthetic gene, using polymerase and ligase enzymes that link pieces of DNA together,[25] as well as methods that anticipated the invention of polymerase chain reaction (PCR).[26]

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Alec Todd – Wikipedia

December 22, 2025

https://en.wikipedia.org/wiki/Alec_Todd

QT:{{”
By 1951, Todd and collaborators at Cambridge had determined by biochemical methods how the backbone of DNA is structured via the successive linking of carbon atoms 3 and 5 of the sugar to phosphates. This helped corroborate Francis Crick and James_Watson’s X-ray structural work published in 1953.[11][12]: 94 [13]: 7–8
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The Garden of Forking Paths – Wikipedia

December 21, 2025

https://en.wikipedia.org/wiki/The_Garden_of_Forking_Paths

QT:{{”
“The Garden of Forking Paths” (original Spanish title: “El jardín de senderos que se bifurcan”) is a 1941 short story by Argentine writer and poet Jorge Luis Borges. ….
The story’s theme has been said to foreshadow the many-worlds interpretation of quantum mechanics.[1][2] I
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Arthur Kornberg – Wikipedia

December 21, 2025

https://en.wikipedia.org/wiki/Arthur_Kornberg

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On the Future of Species

December 21, 2025

Adrian Woolfson’s On the Future of Species for Science?

https://www.penguinrandomhouse.com/books/830520/on-the-future-of-species-by-adrian-woolfson/

bold vision for the future of biological engineering.

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