https://www.ncbi.nlm.nih.gov/pubmed/26771485
http://www.cell.com/cell/fulltext/S0092-8674(15)01569-X
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https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-0992-2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113484/
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materials in http://meetings.gersteinlab.org/2017/10.28/i0gi2017/
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