https://www.nature.com/articles/s41586-021-04269-6
https://twitter.com/MarkGerstein/status/1510065060806283269
Interesting paper, relating de novo mutation rate to epigenetic features. Wonder exactly how this connects to the fact that the background mutation rate in cancer genomes depends strongly on epigenetics.
Important genomic regions mutate less often than do other regions https://www.nature.com/articles/d41586-022-00017-6
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