Posts Tagged ‘x78retwee’

A.I. Is Mastering Language. Should We Trust What It Says? – The New York Times

April 24, 2022

I don’t trust it, but, at the same time, I am willing to let it help me write. Also, suspect this will make grading term papers quite a challenge in the future.
https://www.nytimes.com/2022/04/15/magazine/ai-language.html?smid=tw-share

Rare coding variants in ten genes confer substantial risk for schizophrenia | Nature

April 23, 2022

https://www.nature.com/articles/s41586-022-04556-w

Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature

April 23, 2022

https://www.nature.com/articles/s41586-022-04434-5

Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome

April 22, 2022

https://www.science.org/doi/10.1126/science.abm5847

Mutation bias reflects natural selection in Arabidopsis thaliana | Nature

April 14, 2022

https://www.nature.com/articles/s41586-021-04269-6

https://twitter.com/MarkGerstein/status/1510065060806283269

Interesting paper, relating de novo mutation rate to epigenetic features. Wonder exactly how this connects to the fact that the background mutation rate in cancer genomes depends strongly on epigenetics.

Important genomic regions mutate less often than do other regions https://www.nature.com/articles/d41586-022-00017-6

Commit to transparent COVID data until the WHO declares the pandemic is over

April 14, 2022

Liked the line: “A simple text file would do.” People should be more aware of how useful the most basic of formats is!

https://www.nature.com/articles/d41586-022-00424-9

Life’s Preference for Symmetry Is Like ‘A New Law of Nature’ – The New York Times

April 14, 2022

Interesting paper. Nevertheless, natural designs are still less symmetric than engineered ones. (I think!) Any thoughts on why?

https://www.pnas.org/doi/10.1073/pnas.2113883119

Symmetry and simplicity spontaneously emerge from the algorithmic nature of evolution

https://www.nytimes.com/2022/03/24/science/symmetry-biology-evolution.html

Biologically informed deep neural network for prostate cancer discovery | Nature

April 12, 2022

https://www.nature.com/articles/s41586-021-03922-4

https://twitter.com/SEHanlon/status/1513548800949989377

At #AACR22, @VanAllenLab gives a nice overview of his paper using an interpretable NN model to get insights into determining cancer severity (https://nature.com/articles/s41586-021-03922-4)
Biologically informed deep neural network for prostate cancer discovery

Liked the way he hard-coded specific genes & pathways into the model & looked in detail where the model misclassified specific patients #AACR22 #AACR2022

Also, thought the hard-coding of genes into the model was similar to that in another interpretable AI approach (for brain disease, https://science.org/doi/10.1126/science.aat8464) Could have used the “rank projection trees” from this to highlight important genes #AACR22 #AACR2022

The complete sequence of a human genome

April 10, 2022

https://www.science.org/doi/10.1126/science.abj6987

Congratulations. Looking forward to mapping trillions of reads against CHM13!

The women with superhuman vision – BBC Future

April 10, 2022

https://www.bbc.com/future/article/20140905-the-women-with-super-human-vision