Posts Tagged ‘x78retwee’

COVID antiviral pills: what scientists still want to know

December 18, 2021

QT:{{”
Molnupiravir acts by introducing mutations into the viral genome during viral replication. A metabolite of the drug is picked up by a viral enzyme called RNA-dependent RNA polymerase and incorporated into the viral genome, eventually causing so many errors that the virus can no longer survive.

Paxlovid acts by inhibiting an enzyme that’s needed to process some viral proteins into their final, functional form. But the drug is a combination of an antiviral and another drug, called ritonavir, which helps to prevent enzymes in the liver from breaking down the antiviral before it has a chance to disable the coronavirus. Ritonavir, a component of some HIV treatment cocktails, can affect how some other medications are metabolized by the body.
“}}
Molnupiravir & Paxlovid
https://www.nature.com/articles/d41586-021-03074-5

The controversial new clinical trials that promise faster results | New Scientist

December 18, 2021

https://www.newscientist.com/article/mg25133574-200-the-controversial-new-clinical-trials-that-promise-faster-results/ adaptive trials

Opinion | Why Hospitalizations Are Now a Better Indicator of Covid’s Impact – The New York Times

December 18, 2021

Opinion | Why Hospitalizations Are Now a Better Indicator of Covid’s Impact – The New York Times
https://www.nytimes.com/2021/12/11/opinion/why-hospitalizations-are-now-a-better-indicator-of-covids-impact.html

Why there is no such thing as a healthy diet that works for everyone | New Scientist

December 18, 2021

An interesting paper with implications for personalized nutrition, suggested to me by
@DrGarrettAsh1
https://link.springer.com/article/10.1007%2Fs13300-021-01174-z Gut Microbiome Activity Contributes to Prediction of Individual Variation in Glycemic Response in Adults

Represents an update to “Personalized Nutrition by Prediction of Glycemic Responses” from the
@segal_eran
lab (https://cell.com/fulltext/S0092-8674(15)01481-6)
cell.com
Personalized Nutrition by Prediction of Glycemic Responses

Also, I felt this easy to read
@NewScientist
overview was quite relevant to these works & put them into a larger
context https://newscientist.com/article/mg24732990-600-why-there-is-no-such-thing-as-a-healthy-diet-that-works-for-everyone/ Why there is no such thing as a healthy diet that works for everyone

Mapping the human genetic architecture of COVID-19 | Nature

December 16, 2021

https://www.nature.com/articles/s41586-021-03767-x

SARS-CoV-2 could be lurking in animal hidey-holes | The Economist

December 6, 2021

https://www.economist.com/science-and-technology/hidey-holes-for-sars-cov-2-1/21806334

The Worst of Both Worlds: Zooming From the Office – The New York Times

December 5, 2021

https://www.nytimes.com/2021/11/16/business/return-to-office-hybrid-work.html

How Do You See Inside a Volcano? Try a Storm of Cosmic Particles. – The New York Times

December 5, 2021

https://www.nytimes.com/2021/11/10/science/volcanoes-muons-muography.html

Jeffrey Barrett on Twitter: “Took a look at the spike mutations in B.1.1.529 this evening, and colour coded them (details below)…there is…not much green.🧵 https://t.co/yNHM55oTTH” / Twitter

November 26, 2021

https://twitter.com/jcbarret/status/1463975708770897923

B.1.1.529

There Is Finally a Visible Way Out of the COVID Pandemic

November 24, 2021

https://nymag.com/intelligencer/2021/11/there-is-finally-a-visible-way-out-of-the-covid-pandemic.html