Posts Tagged ‘x78retwee’

COVID antiviral pills: what scientists still want to know

December 18, 2021

QT:{{”
Molnupiravir acts by introducing mutations into the viral genome during viral replication. A metabolite of the drug is picked up by a viral enzyme called RNA-dependent RNA polymerase and incorporated into the viral genome, eventually causing so many errors that the virus can no longer survive.
…
Paxlovid acts by inhibiting an enzyme that’s needed to process some viral proteins into their final, functional form. But the drug is a combination of an antiviral and another drug, called ritonavir, which helps to prevent enzymes in the liver from breaking down the antiviral before it has a chance to disable the coronavirus. Ritonavir, a component of some HIV treatment cocktails, can affect how some other medications are metabolized by the body.
“}}
Molnupiravir & Paxlovid
https://www.nature.com/articles/d41586-021-03074-5

The controversial new clinical trials that promise faster results | New Scientist

December 18, 2021

https://www.newscientist.com/article/mg25133574-200-the-controversial-new-clinical-trials-that-promise-faster-results/ adaptive trials

Opinion | Why Hospitalizations Are Now a Better Indicator of Covid’s Impact – The New York Times

December 18, 2021

Opinion | Why Hospitalizations Are Now a Better Indicator of Covid’s Impact – The New York Times
https://www.nytimes.com/2021/12/11/opinion/why-hospitalizations-are-now-a-better-indicator-of-covids-impact.html

Why there is no such thing as a healthy diet that works for everyone | New Scientist

December 18, 2021

An interesting paper with implications for personalized nutrition, suggested to me by
@DrGarrettAsh1
https://link.springer.com/article/10.1007%2Fs13300-021-01174-z Gut Microbiome Activity Contributes to Prediction of Individual Variation in Glycemic Response in Adults
…
Represents an update to “Personalized Nutrition by Prediction of Glycemic Responses” from the
@segal_eran
lab (https://cell.com/fulltext/S0092-8674(15)01481-6)
cell.com
Personalized Nutrition by Prediction of Glycemic Responses
…
Also, I felt this easy to read
@NewScientist
overview was quite relevant to these works & put them into a larger
context https://newscientist.com/article/mg24732990-600-why-there-is-no-such-thing-as-a-healthy-diet-that-works-for-everyone/ Why there is no such thing as a healthy diet that works for everyone

Mapping the human genetic architecture of COVID-19 | Nature

December 16, 2021

https://www.nature.com/articles/s41586-021-03767-x

SARS-CoV-2 could be lurking in animal hidey-holes | The Economist

December 6, 2021

https://www.economist.com/science-and-technology/hidey-holes-for-sars-cov-2-1/21806334

The Worst of Both Worlds: Zooming From the Office – The New York Times

December 5, 2021

https://www.nytimes.com/2021/11/16/business/return-to-office-hybrid-work.html

How Do You See Inside a Volcano? Try a Storm of Cosmic Particles. – The New York Times

December 5, 2021

https://www.nytimes.com/2021/11/10/science/volcanoes-muons-muography.html

Jeffrey Barrett on Twitter: “Took a look at the spike mutations in B.1.1.529 this evening, and colour coded them (details below)…there is…not much green.🧵 https://t.co/yNHM55oTTH” / Twitter

November 26, 2021

https://twitter.com/jcbarret/status/1463975708770897923

B.1.1.529

There Is Finally a Visible Way Out of the COVID Pandemic

November 24, 2021

https://nymag.com/intelligencer/2021/11/there-is-finally-a-visible-way-out-of-the-covid-pandemic.html