QT:{{”
While rare, mutations that remove or delete sections of DNA in neurexin-1, called deletion mutations, are highly associated with schizophrenia and autism. But these mutations are not straightforward. Almost all affected patients have deletions in different parts of the gene, and because neurexin-1 can code for hundreds of different proteins, deletions in different regions of the gene will affect different proteins.
“This idea of stratifying not just based on symptoms but on genetics and the type of mutations is really the big take-home for informing future precision medicine,” Brennand says.
“}}
linkstream2 microblog 