Archive for the 'SciLit' Category

Statistical and machine learning methods for spatially resolved transcriptomics data analysis | Genome Biology | Full Text

April 29, 2022

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02653-7

Reproducible brain-wide association studies require thousands of individuals | Nature

April 28, 2022

https://www.nature.com/articles/s41586-022-04492-9

Rare coding variants in ten genes confer substantial risk for schizophrenia | Nature

April 23, 2022

https://www.nature.com/articles/s41586-022-04556-w

Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature

April 23, 2022

https://www.nature.com/articles/s41586-022-04434-5

Hartwig

April 23, 2022

the marker paper of the Hartwig Medical Foundation paper.

Pan-cancer whole-genome analyses of metastatic solid tumours https://www.nature.com/articles/s41586-019-1689-y
Peter Priestley, Jonathan Baber, Martijn P. Lolkema, Neeltje Steeghs, Ewart de Bruijn, Charles Shale, Korneel Duyvesteyn, Susan Haidari, Arne van Hoeck, Wendy Onstenk, Paul Roepman, Mircea Voda, Haiko J. Bloemendal, Vivianne C. G. Tjan-Heijnen, Carla M. L. van Herpen, Mariette Labots, Petronella O. Witteveen, Egbert F. Smit, Stefan Sleijfer, Emile E. Voest & Edwin Cuppen
Nature volume 575, pages
210–216 (2019)

There have been numerous follow-up papers since.

Also, the Glioma Longitudinal Analysis (GLASS) Consortium datasets, which are publicly accessible via www.synapse.org/glass.
The first marker paper is here:
https://www.nature.com/articles/s41586-019-1775-1.

The role of dorsolateral and ventromedial prefrontal cortex in the processing of emotional dimensions | Scientific Reports

April 23, 2022

https://www.nature.com/articles/s41598-021-81454-7#:~:text=To%20put%20it%20in%20a,the%20respective%20areas%20does%20hold.
QT:{{”
To put it in a nutshell, the vmPFC is assumed to have a crucial role in emotional processing, whereas the dlPFC is predominantly involved in cognitive control and executive processing.
It is however debatable if such a strict functional distinction of the respective areas does hold.
“}}

Somatic mutation rates scale with lifespan across mammals | Nature

April 22, 2022

https://www.nature.com/articles/s41586-022-04618-z

Cryptic and abundant marine viruses at the evolutionary origins of Earth’s RNA virome

April 22, 2022

https://www.science.org/doi/10.1126/science.abm5847

Quantification of private information leakage from phenotype-genotype data: linking attacks – PubMed

April 18, 2022

https://pubmed.ncbi.nlm.nih.gov/26828419/

Data Sanitization to Reduce Private Information Leakage from Functional Genomics – PubMed

April 18, 2022

https://pubmed.ncbi.nlm.nih.gov/33186529/