Bourne mentions “What Big Data means to me”
(http://jamia.bmj.com/content/21/2/194.extract ) in connection with the creation of a digital ecosystem #ydod2014
Archive for the 'SciLit' Category
What Big Data means to me — Bourne 21 (2): 194 — Journal of the American Medical Informatics Association
September 30, 2014Analysis of noncoding regulatory mutations in cancer
September 29, 2014http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3101.html
An interesting report of potential non-coding drivers without actually doing any wet lab work.
“These methods identify recurrent mutations in regulatory elements upstream of PLEKHS1, WDR74 and SDHD, as well as previously identified mutations in the TERT promoter”. In the text they mention “Khurana et al. also reported WDR74 promoter mutations in 2 of the 20 prostate cancer genomes analyzed”.
PLOS Computational Biology: Spatial Generalization in Operant Learning: Lessons from Professional Basketball
September 29, 2014Spatial Generalization in… Learning: Lessons from… #Basketball http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003623 How past success changes your tendencies to shoot
Describes constructing a learning matrix for how a player will update his tendency to shoot
from a certain region of the court based on his past successes or failures
The Parable of Google Flu: Traps in Big Data Analysis
September 29, 2014Parable of #Google Flu: Traps in #BigData Analysis http://www.sciencemag.org/content/343/6176/1203.summary Replicating results is hard, w/ an ever-changing search algorithm
Blood transciptome paper
September 28, 2014Splicing changes along the blood lineage, good ex. of the
state-of-the-art in human transcriptomics
http://www.sciencemag.org/content/345/6204/1251033.abstract
Science 26 September 2014:
Vol. 345 no. 6204
DOI: 10.1126/science.1251033
Transcriptional diversity during lineage commitment of human blood progenitors
Chen et al.
Phylomemetics—Evolutionary Analysis beyond the Gene
September 21, 2014Phylomemetics—Evolutionary Analysis beyond the Gene
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.1001069 #Phylogenetics for texts, languages & artifacts (w/ recoding)
BoxPlotR: a web tool for generation of box plots
September 21, 2014They published a paper on a web tool to generate box plots !! http://www.nature.com/nmeth/journal/v11/n2/full/nmeth.2811.html QT:{{”
Despite the obvious advantages of the box plot for simultaneous representation of data set and statistical parameters, this method is not in common use, in part because few available software tools allow the facile generation of box plots. For example, the standard spreadsheet tool Excel is unable to generate box plots.
…
M.S. and J.W. conceived of the box plot tool
“}}
Related:
http://bioinformatics.oxfordjournals.org/content/early/2014/01/21/bioinformatics.btu038.abstract
PLOS Computational Biology: Ten Simple Rules of Live Tweeting at Scientific Conferences
September 19, 201410… Rules of Live Tweeting at Sci #Conferences by @eperlste http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003789 Great list but no mention of #crowdsourced note taking
Is ecology explaining less and less?
September 15, 2014Is #ecology explaining less & less? http://news.sciencemag.org/biology/2014/08/ecology-explaining-less-and-less Over 100yr & 18k papers: more #pvalues but falling <r2>. What’s P for this trend?
linkstream2 microblog 