https://www.nytimes.com/2021/09/17/us/fda-pfizer-booster-covid.html
F.D.A. Panel Recommends Pfizer Boosters for Those Over 65 or at Risk – The New York Times
September 19, 2021The tangled history of mRNA vaccines
September 19, 2021Lego Shoes
September 19, 2021Maybe this comparison is like physical chemistry vs chemical physics or chemical biology vs biochemistry!
…
Found it interesting to compare a Lego Adidas to an Adidas Lego https://www.Adidas.com/us/adidas-superstar-x-lego-shoes/H03954.html vs
https://www.Lego.com/en-us/product/adidas-originals-superstar-10282 . Two perspectives on a common object.
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Computational scientists look for lessons learned from the COVID-19 pandemic
September 19, 2021https://cen.acs.org/physical-chemistry/computational-chemistry/Computational-scientists-look-lessons-learned/99/i28
QT:{{”
One computational achievement stands out from the rest—models of the virus’s proteins. In February 2020, with the virus spreading rapidly around the world, structural biologist Jason S. McLellan at the University of Texas at Austin and colleagues at the National Institutes of Health used cryo-electron microscopy (cryo-EM) to make detailed structures of SARS-CoV-2’s spike protein. The virus uses the spike protein to attach to and enter human cells. This protein is a major target for drugs and vaccines. Within weeks of McLellan’s team publishing the cryo-EM data, Rommie Amaro’s group at the University of California San Diego used those structures to create the first computer models of the protein using artificial intelligence and other computational techniques.
In the months that followed, the group used those tools to make more-highly-detailed models of the spike protein. For example, the researchers modeled what the sugars that dot the protein’s surface look like—a feature that cryo-EM can’t capture but that is important for understanding how antibodies or drugs may interact with the protein. Their simulations also showed how the protein’s shape changes to reveal its receptor-binding domain, a region that scientists want to target with therapeutics. The work won Amaro’s group a special kind of Gordon Bell Prize, one of the most prestigious awards in
supercomputing.
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Salience (neuroscience) – Wikipedia
September 18, 2021Over-the-counter COVID-19 tests make big promises. Do they deliver?
September 18, 2021The Promise of Carbon-Neutral Steel | The New Yorker
September 18, 2021Using deep learning to model the hierarchical structure and function of a cell | Nature Methods
September 18, 2021https://www.nature.com/articles/nmeth.4627
interpretable deep learning model
undergrad reporting wiki updated
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https://twitter.com/MarkGerstein/status/1438708035845705729
Recently analyzed (with Jack Chapman) the many undergrads (almost 200) that have worked in the lab over the past years (as summer students, taking research courses, doing theses, &c)
http://INFO.GersteinLab.org/Summary_of_undy_of_undergraduate_involvement
Highlights of the analysis are the great increase in the number of undergrads in the last few years (albeit this is subject to
substantial ascertainment bias) and the shift to more stats & CS majors away from bio. ones.
