Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment | Nature Biotechnology
September 28, 2026Can an AI-designed drug slow aging?
September 28, 2026https://ctrk.klclick.com/l/01M2ZDVD112D4GPK2S1Z8EH3BR_23
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Elysium Abstract
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An AI-designed drug sent six aging clocks backward
In a 12-week phase 2a trial, an AI-designed drug for idiopathic pulmonary fibrosis reduced predicted biological age across six protein-based aging clocks in 42 participants. The findings don’t prove the drug slows aging, but they point to a new way to study it. “This is one of the few concrete examples of a drug largely designed with generative AI,” says Mark Gerstein, Ph.D., Albert L. Williams Professor of Biomedical Informatics at Yale and a member of Elysium’s Scientific Advisory Board. “Moreover, it’s impressive to see how AI was used throughout the whole drug-development process, from upstream target finding to analyzing the downstream trial for results related to longevity.” He adds: “This last use has great promise for aging research, showing how conventional disease trials can be made into dual-purpose designs suitable for studying longevity.” (Nature Biotechnology)
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Source: Whitney Museum of American Art
September 28, 2026https://whitney.org/artists/18614?shem=aimgspe,
Source: Whitney Museum of American Art Carla Gannis
NOT-GM-26-007: Notice of Information: Changes to NIGMS Institutional Basic Biomedical and Clinician Scientist Training Programs
September 28, 2026Relevant to training grants
https://grants.nih.gov/grants/guide/notice-files/NOT-GM-26-007.html
How tech firms hope to beat the backlash against “pervert glasses”
September 27, 2026How tech firms hope to beat the backlash against “pervert glasses”
https://www.economist.com/business/2026/09/24/how-tech-firms-hope-to-beat-the-backlash-against-pervert-glasses
Source: Codeable
September 27, 2026https://www.codeable.io/blog/convert-to-wordpress/?shem=isphc, Codeable BlogWordPress Help
Convert to WordPress: 5 Methods for Your HTML Site
October 9, 2025
How to Rule the World by Theo Baker: 9780593832837
September 27, 2026Marc Tessier-Lavigne – Wikipedia
September 27, 2026chewing gum to open eustachian tube – Google Search
September 27, 2026https://www.google.com/search?q=chewing+gum+to+open+eustachian+tube&oq=gum+chewing+to+open+eu&gs_lcrp=EgZjaHJvbWUqCAgBEAAYFhgeMgYIABBFGDkyCAgBEAAYFhgeMg0IAhAAGIYDGIAEGIoFMg0IAxAAGIYDGIAEGIoFMgoIBBAAGIAEGKIEMgoIBRAAGIAEGKIEMgcIBhAAGO8F0gEIODI2OWowajSoAgGwAgHxBZ0GY9sd5_898QWdBmPbHef_PQ&sourceid=chrome&source=chrome.ob&ie=UTF-8 QT:{{” Chewing gum helps open your Eustachian tubes by stimulating saliva production and causing you to swallow repeatedly.How It WorksMore Saliva: Chewing makes your mouth produce extra
saliva.Frequent Swallowing: Every time you swallow, the muscles around your throat activate to open your Eustachian tubes.Pressure Balance: Opening the tubes lets air flow in or out to equalize the pressure between your middle ear and the outside.Other Ways to Open Your EarsYawn: Forcing a big yawn stretches the throat muscles and pops the ears.Valsalva Maneuver: Pinch your nose shut, keep your mouth closed, and blow air out very gently.Toynbee Maneuver: Pinch your nose closed and swallow a sip of water.Suck on Candy: Hard candies or mints create the same swallowing action as gum.”}}
