Jacopo Annese – The Brain Preservation Foundation
March 5, 2018New GWAS SCZ loci (nature genetics 2018)
March 5, 2018Common #schizophrenia alleles are enriched in mutation-intolerant genes & in regions under strong background selection
https://www.nature.com/articles/s41588-018-0059-2 50 novel SCZ loci & 145 loci in total, from #GWAS – associated w/ 33 candidate causal genes
QT:{{”
We report a new genome-wide association study of schizophrenia (11,260 cases and 24,542 controls), and through meta-analysis with existing data we identify 50 novel associated loci and 145 loci in total. Through integrating genomic fine-mapping with brain expression and chromosome conformation data, we identify candidate causal genes within 33 loci.
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nature Genetics (2018)
doi:10.1038/s41588-018-0059-2
Glowing Auras and ‘Black Money’: The Pentagon’s Mysterious U.F.O. Program – The New York Times
March 5, 2018Glowing Auras & Black Money: The Pentagon’s Mysterious #UFO Program
https://www.nytimes.com/2017/12/16/us/politics/pentagon-program-ufo-harry-reid.html Rather incredible that this exists. I’m sure it’ll spawn many movies…
dynamic LDA
March 5, 2018Dynamic Topic Models
https://mimno.infosci.cornell.edu/info6150/readings/dynamic_topic_models.pdf Classic work by @Blei_lab & J Lafferty adapts the #LDA formalism describing documents in terms of latent topics – to allow these to evolve over time
