Posts Tagged ‘dw’

« Older posts

science

January 8, 2022

Published: 05 January 2022
Decoding gene regulation in the fly brain
Jasper Janssens, Sara Aibar, Ibrahim Ihsan Taskiran, Joy N. Ismail, Alicia Estacio Gomez, Gabriel Aughey, Katina I. Spanier, Florian V. De Rop, Carmen Bravo González-Blas, Marc Dionne, Krista Grimes, Xiao Jiang Quan, Dafni Papasokrati, Gert Hulselmans, Samira Makhzami, Maxime De Waegeneer, Valerie Christiaens, Tony Southall & Stein Aerts Nature (2022)

Nature paper today on Fly brain GRNs, https://doi.org/10.1038/s41586-021-04262-z

Some integrative analyses might be useful…

Posted in SciLit | Leave a Comment »
Tags: , , , ,

neuroDEVELOPMENTS: Neuroscience Research to Clinical Relevance

March 31, 2019

https://mailchi.mp/add7f814b67d/neurodevelopments-720229
https://www.libd.org/neurodevelopments/

the Lieber’s neuroDEVELOPMENTS newsletter, which features the PsychENCODE paper

Posted in - | Leave a Comment »
Tags: , , , , ,

Read Light Up Your Imagination Argus Large Poster by Trend Enterprises: Language Arts: K12SchoolSupplies.net

February 15, 2019

https://www.k12schoolsupplies.net/Read-Light-Up-Your-Imagination-Argus-Large-Poster-p/t-a67365.htm

Posted in InterestingImages | Leave a Comment »
Tags: , , , ,

Nature 03142018 Single cell rnaseq of development of human brain Pfc

March 18, 2018

https://www.nature.com/articles/nature25980

A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex

Suijuan Zhong
, Shu Zhang
[…]
Xiaoqun Wang
Nature
doi:10.1038/nature25980

Posted in SciLit | Leave a Comment »
Tags: , , , , , ,

New GWAS SCZ loci (nature genetics 2018)

March 5, 2018

Common #schizophrenia alleles are enriched in mutation-intolerant genes & in regions under strong background selection
https://www.nature.com/articles/s41588-018-0059-2 50 novel SCZ loci & 145 loci in total, from #GWAS – associated w/ 33 candidate causal genes

QT:{{”
We report a new genome-wide association study of schizophrenia (11,260 cases and 24,542 controls), and through meta-analysis with existing data we identify 50 novel associated loci and 145 loci in total. Through integrating genomic fine-mapping with brain expression and chromosome conformation data, we identify candidate causal genes within 33 loci.
“}}

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nature Genetics (2018)
doi:10.1038/s41588-018-0059-2

Posted in SciLit | Leave a Comment »
Tags: , , , , , , , , ,

A survey of human brain transcriptome diversity at the single cell level

June 27, 2017

Brain #transcriptome diversity at the single cell level
http://www.PNAS.org/content/112/23/7285 Has useful gene-exp. profiles of specific neural cell types

has profiles for 185 biomarker genes for 6 cell types

Posted in SciLit | Leave a Comment »
Tags: , , , , , ,

R package: variancePartition

November 13, 2016

https://bioconductor.org/packages/release/bioc/html/variancePartition.html

new tool in psychencode meeting

Posted in - | Leave a Comment »
Tags: , , , ,

Authorship solution

July 28, 2016

A solution to a perennial problem: Co-first “author ordering determined by coin flip” – eg
http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201604431/full & https://arxiv.org/pdf/1412.6980v8.pdf

similar
https://arxiv.org/pdf/1412.6980v8.pdf
∗Equal contribution. Author ordering determined by coin flip over a Google Hangout.

Posted in - | Leave a Comment »
Tags: , , , , ,

Similarity network fusion for aggregating data types on a genomic scale : Nature Methods : Nature Publishing Group

February 9, 2016

Similarity #network fusion for aggregating data types
http://www.nature.com/nmeth/journal/v11/n3/full/nmeth.2810.html Combines mRNA, miRNA & gene fusions to classify cancer subtypes http://compbio.cs.toronto.edu/SNF/SNF

Posted in SciLit | Leave a Comment »
Tags: , , , , , ,

Single-cell ChIP-seq

October 23, 2015

#Singlecell ChIPseq reveals…subpopulations defined by chromatin statehttp://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.3383.html Sparse data: on order of 1K uniq. reads/cell

http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.3383.html

Posted in SciLit | Leave a Comment »
Tags: , , , ,

« Older posts