Looks useful!
http://nar.oxfordjournals.org/content/early/2013/11/24/nar.gkt1188
Posts Tagged ‘1000g’
1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans
December 1, 2013PacBio data for CHM1 genome
October 24, 2013It look as though the data are now ready for download
http://datasets.pacb.com/2013/Human10x/READS/index.html along with a brief description of the data
http://blog.pacificbiosciences.com/2013/10/data-release-long-read-shotgun.html
Gene intolerance scores in a Plos Gen paper
August 26, 2013http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003709#pgen-1003709-g006
This paper discusses gene intolerance score — very similar to depletion of common polymorphisms. They don’t analyze non-coding regions — this is using exome data only. Blue for tolerant and red for intolerant (see Figure 1) .
Q&A: David Altshuler on How to Share Millions of Human Genomes – ScienceInsider
June 11, 2013http://news.sciencemag.org/scienceinsider/2013/06/-qa-david-altshuler-on-how-to-sh.html
But how will a little player participate in this? MT @gtyrelle: Q&A: on How to Share Millions of Human Genomes http://bit.ly/19jlKNs
Genome-wide inference of natural selection on human transcription factor binding sites
June 10, 2013http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2658.html Uses only CG data for variation, only TFBS data form ENCODE. QT:”the binding sites of several transcription factors show clear evidence of adaptation.”
Comment on “Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions ”
May 18, 2013Non-coding variation review
November 25, 2012The population genetics of the Jewish people. Hum Genet. 2012 – PubMed – NCBI
November 3, 2012Hum Genet. 2012 Oct 10.
Ostrer H, Skorecki K.
Departments of Pathology and Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.
http://www.ncbi.nlm.nih.gov/pubmed/23052947
Admixture analysis
linkstream2 microblog 