Posts Tagged ‘1000g’

1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures of natural selection in modern humans

December 1, 2013

Looks useful!

PacBio data for CHM1 genome

October 24, 2013

It look as though the data are now ready for download along with a brief description of the data

Gene intolerance scores in a Plos Gen paper

August 26, 2013
This paper discusses gene intolerance score — very similar to depletion of common polymorphisms. They don’t analyze non-coding regions — this is using exome data only. Blue for tolerant and red for intolerant (see Figure 1) .

Q&A: David Altshuler on How to Share Millions of Human Genomes – ScienceInsider

June 11, 2013
But how will a little player participate in this? MT @gtyrelle: Q&A: on How to Share Millions of Human Genomes

Genome-wide inference of natural selection on human transcription factor binding sites

June 10, 2013 Uses only CG data for variation, only TFBS data form ENCODE. QT:”the binding sites of several transcription factors show clear evidence of adaptation.”

Comment on “Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions ”

May 18, 2013

Non-coding variation review

November 25, 2012

The population genetics of the Jewish people. Hum Genet. 2012 – PubMed – NCBI

November 3, 2012

Hum Genet. 2012 Oct 10.
Ostrer H, Skorecki K.
Departments of Pathology and Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.

Admixture analysis

1000 Genomes Project moves researchers closer to personalized medicine | Fox News

November 2, 2012

The 1000 Genomes Project more than doubles catalog of human genetic variation, October 31, 2012 News Release – National Institutes of Health (NIH)

November 2, 2012