http://www.cell.com/abstract/S0092-8674%2812%2901061-6?utm_source=ECE001&utm_campaign=&utm_content=&utm_medium=email&bid=OV63V3F:KK4SNSD 23 whole genome tumor/normal pairs
This was covered in NYT a few days ago
http://www.nytimes.com/2012/09/10/health/research/for-a-lung-cancer-drug-treatment-may-be-within-reach.html No direct access to ‘vcf’ files.
Here is the link to the 21 Breast Cancer genomes:
http://www.ncbi.nlm.nih.gov/pubmed/22608084
Found hotspots of mutation….
Genome sequence data have been deposited at the European Genome-Phenome Archive (http://www.ebi.ac.uk/ega/ at the EBI) with accession number EGAD00001000138. SNP6 array data have been deposited with ArrayExpress Archive (EBI, accession number E-MTAB-1087).
Seem to have cancer SNV calls all over the genome.
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11273.html
http://www.cell.com/retrieve/pii/S009286741200640X?cc=y
Transcribed pgenes perhaps acting as ceRNAs very tissue specific, in a variety of cancers
Most less conservative threshold on calling transcription than in encodeprodpgenes
3) A Life-Death Predictor Adds to a Cancer’s Strain
http://www.nytimes.com/2012/07/10/health/genetic-test-changes-game-in-cancer-prognosis.html
1) In Gene Sequencing Treatment for Leukemia, Glimpses of the Future – NYTimes.com
http://www.nytimes.com/2012/07/08/health/in-gene-sequencing-treatment-for-leukemia-glimpses-of-the-future.html?pagewanted=all
2) A New Treatment’s Tantalizing Promise Brings Heartbreaking Ups and Downs
http://www.nytimes.com/2012/07/09/health/new-frontiers-of-cancer-treatment-bring-breathtaking-swings.html?pagewanted=all
2) A New Treatment’s Tantalizing Promise Brings Heartbreaking Ups and Downs
http://www.nytimes.com/2012/07/09/health/new-frontiers-of-cancer-treatment-bring-breathtaking-swings.html?pagewanted=all
3) A Life-Death Predictor Adds to a Cancer’s Strain
http://www.nytimes.com/2012/07/10/health/genetic-test-changes-game-in-cancer-prognosis.html
1) In Gene Sequencing Treatment for Leukemia, Glimpses of the Future – NYTimes.com
http://www.nytimes.com/2012/07/08/health/in-gene-sequencing-treatment-for-leukemia-glimpses-of-the-future.html?pagewanted=all
1) In Gene Sequencing Treatment for Leukemia, Glimpses of the Future – NYTimes.com
http://www.nytimes.com/2012/07/08/health/in-gene-sequencing-treatment-for-leukemia-glimpses-of-the-future.html?pagewanted=all
2) A New Treatment’s Tantalizing Promise Brings Heartbreaking Ups and Downs
http://www.nytimes.com/2012/07/09/health/new-frontiers-of-cancer-treatment-bring-breathtaking-swings.html?pagewanted=all
3) A Life-Death Predictor Adds to a Cancer’s Strain
http://www.nytimes.com/2012/07/10/health/genetic-test-changes-game-in-cancer-prognosis.html
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