Could baby’s first bacteria take root before birth?
https://www.Nature.com/articles/d41586-018-00664-8 Interesting discussion of the controversy around detecting trace exogenous sequences in human tissues. Perhaps relevant to #exRNA?
Posts Tagged ‘exrna’
Could baby’s first bacteria take root before birth?
April 21, 2018Glypican-1 identifies cancer exosomes and detects early pancreatic cancer : Nature : Nature Publishing Group
August 16, 2015[Protein] Glypican-1 [uniquely] identifies [circulating] cancer #exosomes & detects…cancer
http://www.nature.com/nature/journal/v523/n7559/full/nature14581.html Maybe also for @exRNA
QT:{{”
Exosomes are lipid-bilayer-enclosed extracellular vesicles that contain proteins and nucleic acids. They are secreted by all cells and circulate in the blood. Specific detection and isolation of
…we identify a cell surface
proteoglycan, glypican-1 (GPC1), specifically enriched on
cancer-cell-derived exosomes. GPC1+ circulating exosomes (crExos) were monitored …”}}
http://www.nature.com/nature/journal/v523/n7559/full/nature14581.html
Invest in Exosomes Before Wall Street Does
June 26, 2015Invest in Exosomes Before Wall Street
http://www.cheatsheet.com/life/health/invest-in-exosomes-before-wall-street-does.html They’re “akin to the Twitter of cells because of” their intercellular messages
QT:{{”
James McCullough, chief executive at privately held Exosome
Diagnostics, appropriately has dubbed exosomes as “the body’s Federal Express system.” Perhaps more succinctly, Dr. Douglas Taylor of Exosome Sciences, a subsidiary of Aethlon Medical (OTCBB:AEMD), has said that exosomes are akin to the “Twitter of cells” because of the messages they deliver from cell to cell.
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CrowdFlower | People-powered Data Enrichment Platform
November 11, 2014Crowd-sourcing w AMZN mechanical turk
also odesk
http://www.behind-the-enemy-lines.com/2012/02/mturk-vs-odesk-my-experiences.html
My notes from a meeting whirlwind in early Nov. – CSHL Biological Data Science, PCAWG & exRNA (i0biods14,i0pcawg14)
November 11, 2014i0biods14 => #biodata14
i0pcawg14 => i0pcawg14+exrna
https://storify.com/markgerstein/favorite-tweets-from-biological-data-science-i0bio
https://linkstream2.gerstein.info/tag/i0pcawg14
https://linkstream2.gerstein.info/tag/i0biods14
http://lectures.gersteinlab.org/summary/nc-annotation-sect-from–PAWG-2-5-9-14_prep_for_Boston_mtg
The go-between: Life’s unexpected messenger – life – 15 September 2014 – New Scientist
October 3, 2014The go-between: Life’s unexpected
messengerhttp://www.newscientist.com/article/mg22329860.400-the-gobetween-lifes-unexpected-messenger.html Overview connecting many flavors of #RNA – ie RNAi, siRNA, miRNA & @exRNA
Some bits unclear though – in relation to boundaries betw. siRNA & exRNA
QT:{{”
The RNA in cells is far more mobile than we thought (Image: Renaud Vigourt)
Far from staying put, RNA – the less famous cousin of DNA – can roam far afield, carrying information to other cells in the body and even to other animals
UNDER the soil of the cornfield, the rootworm larvae emerge from their eggs and crawl in search of roots to munch on. But their mother chose the wrong field to lay her eggs in. There’s something special about the maize here – it’s armed with a smart weapon designed to target the rootworms.
As the larvae feed, this weapon is released from the plant and enters their gut cells. There it halts production of a vital protein by blocking one specific gene. In the hours that follow, this “gene silencing” weapon spreads to other cells in the larvae’s bodies. At first there is no …
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Mirsynergy: detecting synergistic miRNA regul… Bioinformatics. 2014 – PubMed – NCBI
July 19, 2014Mirsynergy: detecting synergistic #miRNA regulatory modules by… neighborhood expansion
http://www.ncbi.nlm.nih.gov/pubmed/24894504 creates overlapping clusters
Use of ontologies in RNAseq data analysis
December 16, 2013came across this paper: http://genomebiology.com/content/11/2/R14, which uses GO for RNA-seq data analysis
looks interesting – GoSeq !
Interesting review on exRNA
October 2, 2013mostly focussed on microRNAs, but it goes into the role of exRNAs on cancer:
http://www.frontiersin.org/Journal/10.3389/fgene.2013.00173/abstract
linkstream2 microblog 