https://www.cell.com/patterns/pdf/S2666-3899(21)00064-7.pdf
OBH – overfitting brain hypothesis
Posts Tagged ‘neurosci’
Scientists have published an atlas of the brain
December 11, 2023Neurons are not the only brain cells that think | The Economist
September 4, 2023astrocyte
QT:{{”
Autism is one. In 2017 Ishizuka Kanako of the Nagoya Institute of Technology, in Japan, found a link between an increased risk of autism and the presence of a pair of genetic variants known to disrupt, in microglia, the expression of a protein called cx3cr1. And in 2020 Xu Zhixiang of Scripps Research, in San Diego, showed a range of microglial protein-synthesis problems cause autism-like symptoms in mice.
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Many researchers now talk of “tripartite” synapses as being standard in the brain. Their transistor-like three-element composition has one part (the astrocyte) which acts like a transistor’s “base” connection, regulating the passage of signals between the other two (the neurons, the equivalents of a transistor’s “emitter” and “collector”). Since transistors form the logic gates of computers, that is intriguing. “}}
Can A.I. Treat Mental Illness? | The New Yorker
May 13, 2023“If You Understand How the Brain Works, You Can Reach Anyone”
May 13, 2023https://hbr.org/2017/03/if-you-understand-how-the-brain-works-you-can-reach-anyone
Beard, Alison. (2017). If You Understand How the Brain Works, You Can Reach Anybody. Harvard Business Review, Mar/Apr 2017, Vol. 95 Issue 2, p 60‐62.
QT:{{”
People who express certain genes in the dopamine system tend to be curious, creative, spontaneous, energetic, and mentally flexible. They are risk-takers and seek novelty. People who have high serotonin activity (or who take SSRI antidepressants) are more sociable, more eager to belong. They’re quite traditional in their values and less inclined toward exploration. People expressive of the testosterone system are tough-minded, direct, decisive, skeptical, and assertive. They tend to be good at what we called rule-based systems—engineering, computers, mechanics, math, and music. And people who are expressive of the estrogen/oxytocin system tend to be intuitive, imaginative, trusting, empathetic, and contextual long-term thinkers. They are sensitive to people’s feelings, too, and typically have good verbal and social skills.
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Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution – ScienceDirect
November 25, 2022https://www.sciencedirect.com/science/article/pii/S0092867422012582
https://twitter.com/ry_lister/status/1587101557010489344
Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution
Author links open overlay panelCharles A.Herring1210Rebecca
K.Simmons1210SaskiaFreytag1210DanielPoppe1210Joel
J.D.Moffet1JahnviPflueger12SamBuckberry12Dulce
B.Vargas-Landin12OlivierClément12Enrique GoñiEcheverría1Gavin J.Sutton3AlbaAlvarez-Franco4RuiHou1ChristianPflueger12KerrieMcDonald5Jose M.Polo67Alistair R.R.Forrest1Anna K.Nowak8…RyanLister1211
How neurons really work is being elucidated | The Economist
August 3, 2022Is a neuron 1 or 256 perceptrons?
https://www.economist.com/science-and-technology/2022/06/29/how-neurons-really-work-is-being-elucidated
Why is the human brain so difficult to understand? We asked 4 neuroscientists.
July 31, 2022QT:{{”
Nearly 100 years ago, physicist Emerson Pugh famously said, “If the human brain were so simple that we could understand it, we would be so simple that we couldn’t.”
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Liked the quote: “If the human brain were so simple that we could understand it, we would be so simple that we couldn’t.”
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