Posts Tagged ‘pseudogenes’
Why rodent pseudogenes refuse to retire
November 23, 2012Cell – Expressed Pseudogenes in the Transcriptional Landscape of Human Cancers
July 14, 2012http://www.cell.com/retrieve/pii/S009286741200640X?cc=y
Transcribed pgenes perhaps acting as ceRNAs very tissue specific, in a variety of cancers
Most less conservative threshold on calling transcription than in encodeprodpgenes
Landscape of Somatic Retrotransposition in Human Cancers – Science
July 5, 2012http://www.sciencemag.org/content/early/2012/06/27/science.1222077.abstract
Park lab led analysis of TCGA data
primate OR pseudogene links
June 22, 2012links to the correction/retraction of the Gilad et al. paper on primate olfactory receptors:
http://www.plosbiology.org/article/info%3Adoi%2F10.1371%2Fjournal.pbio.0050148
Matsui et al. paper looking at genome-wide ORs:
http://mbe.oxfordjournals.org/content/27/5/1192.short
A general lack of compensation for gene dosage in yeast
June 10, 2012http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890323/?tool=pubmed
Interesting in relation to duplication, numbers of pseudogenes and gene expression levels.
Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
June 10, 2012http://www.pnas.org/content/106/18/7507.long
effects of polymorphisms in uORFs in the human population… perhaps worth a larger survey
pseudogenes that might have saved us !
June 6, 2012http://www.sciencedaily.com/releases/2012/06/120604155554.htm?fb_ref=.T829TjfxGmI.like&fb_source=home_oneline Specific inactivation of two immunomodulatory SIGLEC genes during human evolution
http://www.pnas.org/content/early/2012/05/30/1119459109.abstract
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