Posts Tagged ‘quote’

Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes

July 2, 2016

#SingleCell Coexpression…Reveals Distinct Func. Modules [v clustering bulk RNAseq]… & Clinical Outcomes [in GBM]
http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004892

QT:{{”
We found that the co-expressed genes observed in single cells and bulk tumors have little overlap and show distinct characteristics. The co-expressed genes identified in bulk tumors tend to have similar biological functions, and are enriched for intrachromosomal
interactions with synchronized promoter activity. In contrast, single-cell co-expressed genes are enriched for known protein-protein interactions, and are regulated through interchromosomal interactions. “}}

What the Science of Touch Says About Us

June 27, 2016

Feel Me by @AdamGopnik
http://www.NewYorker.com/magazine/2016/05/16/what-the-science-of-touch-says-about-us It’s easier for AI to win at chess than move pieces on the board – cf http://www.NYTimes.com/1997/05/13/opinion/l-how-smart-can-it-be-084328.html

Sensory Studies
MAY 16, 2016 ISSUE
Feel Me
What the new science of touch says about ourselves.
BY ADAM GOPNIK

QT:{{”
““Haptic intelligence is vital to human intelligence,” she concludes. “It’s not just dexterity. It’s finding your way in the world: it’s embodiment, emotion, attack. Haptic intelligence is human
intelligence. We’re just so smart with it that we don’t know it yet. It’s actually much harder to make a chess piece move correctly—to pick up the piece and move it across the board and put it down
properly—than it is to make the right chess move.” She adds, slyly, “When I took A.I. as a student, I was so dismayed to find that most A.I. is just stupid brute force, just running through the
possibilities a machine can look at quickly. Computer chess looks intelligent, but it’s under-the-hood stupid. Reaching and elegantly picking up the right chess piece fluidly and having it land in the right place in an uncontrolled environment—that’s hard. Haptic intelligence is an almost irreproducible miracle! Because people are so good at that, they don’t appreciate it. Machines are good at finding the next move, but moving in the world still baffles them.”” “}}

After Einstein: The Dark Mysteries

June 20, 2016

After Einstein: Dark Mysteries by @SheerPriya
http://www.nybooks.com/articles/2016/06/09/after-einstein-the-dark-mysteries/ Notes sightings of Vulcan until relatively explained Mercury’s orbit http://www.nybooks.com/articles/2016/06/09/after-einstein-the-dark-mysteries/

nice description of gravity waves & black holes for the un-initiated QT:{{”
numerous claimed and reported sightings on several continents of the fictional planet Vulcan… [until general relatively]
“}}

Photo 51 – Wikipedia, the free encyclopedia

June 12, 2016

QT:{{”

Photograph 51 is the nickname given to an X-ray diffraction image of DNA taken by Raymond Gosling in May 1952, working as a PhD student under the supervision of Rosalind Franklin,[1][2][3][4] at King’s College London inSir John Randall’s group. It was critical evidence[5] in identifying the structure of DNA.[6]

James Watson was shown the photo by Maurice Wilkins without Rosalind Franklin’s approval or knowledge (although by this time Gosling had returned to the supervision of Wilkins). Along with Francis Crick, Watson used characteristics and features of Photo 51 to develop the chemical model of the DNA molecule. In 1962, the Nobel Prize in Physiology or Medicine was awarded to Watson, Crick and Wilkins. The prize was not awarded to Franklin; she had died four years earlier, and the Nobel Prize’s rules require that it be awarded only to living persons.[7]

“}}

https://en.wikipedia.org/wiki/Photo_51

Oswald Avery – Wikipedia, the free encyclopedia

June 12, 2016

QT:{{”
The Avery–MacLeod–McCarty experiment was an experimental
demonstration, reported in 1944 by Oswald Avery, Colin MacLeod, andMaclyn McCarty, that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it wasproteins that served the function of carrying genetic information (with the very word protein itself coined to indicate a belief that its function was primary).
“}}

https://en.wikipedia.org/wiki/Oswald_Avery

The Biological State: Nazi Racial Hygiene, 1933–1939

June 11, 2016

QT:{{”
Nazism was “applied biology,” stated Hitler deputy Rudolf Hess. During the Third Reich, a politically extreme, antisemitic variation of eugenics determined the course of state policy.
“}}

Turns Out All Your Friends Have More Friends Than You

June 9, 2016

All Your Friends Have More Friends Than You
http://nymag.com/scienceofus/2016/05/turns-out-all-your-friends-have-more-friends-than-you.html Twist on social #networks having a #powerlaw degree distribution
QT:{{”
The paradox arises because numbers of friends people have are distributed in a way that follows a power law rather than an ordinary linear relationship. So most people have a few friends while a small number of people have lots of friends.
“}}

In dramatic statement, European leaders call for ‘immediate’ open access to all scientific papers by 20 20

June 7, 2016

European leaders call for immediate #OpenAccess to all sci papers by
’20 http://www.sciencemag.org/news/2016/05/dramatic-statement-european-leaders-call-immediate-open-access-all-scientific-papers Spearheaded by Holland, home to Elsevier

QT:{{”
“goal is part of a broader set of recommendations in support of open science, a concept that also includes improved storage of and access to research data. The Dutch government, which currently holds the rotating E.U. presidency, had lobbied hard for Europe-wide support for open science, as had Carlos Moedas, the European commissioner for research and innovation.
….
We probably don’t realize it yet, but what the Dutch presidency has achieved is just unique and huge,” Moedas said
“}}

Hugo de Vries – Wikipedia, the free encyclopedia

May 23, 2016

QT:{{”
He is known chiefly for suggesting the concept of genes, rediscovering the laws of heredity in the 1890s while unaware of Gregor Mendel’s work, for introducing the term “mutation”, and for developing a mutation theory of evolution.
“}}

https://en.wikipedia.org/wiki/Hugo_de_Vries

A Disabilities Program That ‘Got Out of Hand’

May 17, 2016

QT:{{"

“By 1992, half of Dalton’s students entering fourth grade had already received remedial help. Several Dalton teachers describe their classrooms as being overrun by specialists. One teacher, who had half her class diagnosed with learning problems, says she simply gave up arguing with the specialists and used the Fisher Landau program for her entire class.

Other teachers battled back, refusing to let the specialists in their rooms. When teachers gathered, they joked about how long it would be before the entire primary school was diagnosed with learning disabilities. Jeannie Wang, a former Dalton kindergarten teacher, said: "If you dig hard enough in any kid, you’ll find a problem. If you want to have something to write down, you’ll find something to write down."

Then, in fall 1992, it abruptly ended. The kindergarten teachers revolted and refused to use the screening test, saying too many children were being given harmful and unreliable labels. Naomi Hill, the new primary school principal with a different educational philosophy, dismantled much of the Fisher Landau program.

Instantly, learning disabilities at Dalton plummeted. This year, half a dozen kindergartners are getting extra help from specialists; about 15 percent in first through third grades receive help.

That such a major shift could occur twice in one place in a decade is a stunning commentary on how subjective the identification of learning disabilities can be and how little is known about them. Did It Help?

Despite the hundreds of thousands of dollars Mrs. Landau paid the universities, no one today can say with objective certainty whether the remedial program actually helped Dalton students. "We can’t answer that question," said Steven Peverly, one of three Columbia researchers who worked four years on the project. "In the field of education there’s this problem with research. People don’t think about setting up controls. It’s not like science."”
"}}