Posts Tagged ‘stress’

Protein-structure-guided discovery of functional mutations across 19 cancer types : Nature Genetics : Nature Research

December 11, 2016

Protein-structure-guided discovery of functional mutations across 19 #cancer types http://www.nature.com/ng/journal/v48/n8/abs/ng.3586.html Cancer3D relates SNVs to drugs

http://www.nature.com/ng/journal/v48/n8/abs/ng.3586.html

Ambry Freely Providing Aggregate Allele-Frequency Data From 10,000 Sequenced Cancer Patients

March 27, 2016

.@AmbryGenetics…Providing Aggregate Allele-Freq. Data From 10k Sequenced Cancer
Patientshttps://www.genomeweb.com/sequencing-technology/ambry-freely-providing-aggregate-allele-frequency-data-10000-sequenced-cancer ExAC-like presentation

Why Human Disease-Associated Residues Appear as the Wild-Type in Other Species: Genome-Scale Structural Evidence for the Compensation Hypothesis

September 14, 2015

Why human disease-associated residues appear as WT in other species http://mbe.oxfordjournals.org/content/31/7/1787.abstract Compensation by their 3D structural neighbors